Dihydroceramide Desaturase Inhibition by a Cyclopropanated Dihydroceramide Analog in Cultured Keratinocytes

Table 1

N-acyl metabolites of 1 identified by ESI-MS in lipid extracts of differentiated keratinocytes.

Fatty acid type	𝑚/𝑧 of molecular ion [M + H]^+
14 : 0	440.4
16 : 0	468.4
16 : 0h^a	484.4
18 : 0	496.4
18 : 1	494.4
22 : 0	552.4
24 : 1	578.5
26 : 0	608.5
28 : 1	634.5

^aα-hydroxy fatty acid.