Figure 4: oxLDL and cholesterol depletion have similar effects on realignment of endothelial cells in the direction of the flow. Left column: typical images of control, oxLDL-treated cells (10 μg/mL oxLDL, 1 h), and MβCD-treated cells (5 mM, 1 h) exposed to 10 dyn/cm2 for 12 hours. Right column: typical images of F-actin structure in the same cell populations. Arrow indicates the direction of flow. Adapted from [24].