Potent Inhibition of Acid Ceramidase by Novel B-13 Analogues

Figure 5

Activity of aCDase in the presence of 2.5 μM of the novel analogues DP24 a–c and DP25 a,c as well as B13 and its enantiomer ent-B13. All experiments were conducted as triplicates and repeated at least once. 𝑃-values (two-tailed, in order of appearance):  .007,  .003,  .083,  .006,  .009,  .027,  .026.