Review Article

Sphingolipid Metabolic Pathway: An Overview of Major Roles Played in Human Diseases

Figure 6

Status of different compartments in hepatocellular carcinoma. Hepatocellular carcinoma is a case of proliferative scenario mediated through downregulation of ceramide production (in compartment C-3(x)) and upregulation (⚫) of complex sphingolipid biosynthesis in order to quench the proapoptotic ceramide.
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