Roles of Fatty Acid Oversupply and Impaired Oxidation in Lipid Accumulation in Tissues of Obese Rats

Table 2

³H-R-BrP clearance (𝐾^∗_𝑓) and ¹⁴C-P clearance into storage products (𝐾_𝑓𝑠) in individual tissues of lean and obese Zucker rats in vivo.

	𝐾^∗𝑓 (mL 100 g^−1 min^−1)		𝐾𝑓𝑠 (mL 100 g^−1 min^−1)
	Lean	Obese	Lean	Obese
Cerebellum	0.46±0.05	0.48±0.04	0.87±0.07	0.79±0.05
Liver	37.5±2.8	32.3±2.3	45.9±4.4	38.9±2.8
WAT	0.69±0.05	0.70±0.06	1.6±0.1	1.4±0.2
BAT	7.2±0.6	3.6±0.5^∗∗∗	9.4±1.0	7.8±1.4
Heart	29.3±2.8	16.5±1.4^∗∗	15.5±1.2	17.0±3.3

𝐾^∗_𝑓 indexes the ability of the tissue to take up and utilize FA (for both oxidation and storage); 𝐾_𝑓𝑠 indexes the ability to store FA. Data are mean ± SE (𝑛=6 per group).
^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 versus Lean.