Roles of Fatty Acid Oversupply and Impaired Oxidation in Lipid Accumulation in Tissues of Obese Rats

Table 4

Indices of FA utilization (𝑅^∗_𝑓) and FA incorporation into storage (𝑅_𝑓𝑠) in individual tissues of lean and obese Zucker rats in vivo.

	𝑅^∗𝑓 (μmol 100 g^−1 min^−1)		𝑅𝑓𝑠 (μmol 100 g^−1 min^−1)
	Lean	Obese	Lean	Obese
Cerebellum	0.14±0.01	0.32±0.04^∗∗∗	0.26±0.03	0.54±0.07^∗∗∗
Liver	11.5±1.4	21.8±3.1^∗∗	13.7±1.1	26.3±3.5^∗∗
WAT	0.21±0.02	0.47±0.07^∗∗	0.47±0.03	0.93±0.16^∗
BAT	2.02±0.14	2.37±0.44	2.62±0.26	5.28±1.25
Heart	9.1±1.3	10.2±1.0	4.7±0.4	10.1±1.2^∗∗∗

𝑅^∗_𝑓 is an index of FA utilization rate (for both oxidation and storage) in the tissue. 𝑅_𝑓𝑠 indexes flux of plasma FA into storage. Data are mean ± SE (𝑛=6 per group).
^∗𝑃<0.05, ^∗∗𝑃<0.01, ^∗∗∗𝑃<0.001 versus Lean.