Journal of Lipids / 2013 / Article / Tab 1

Research Article

Association of RXR-Gamma Gene Variants with Familial Combined Hyperlipidemia: Genotype and Haplotype Analysis

Table 1

Clinical characteristics of FCHL patients and controls.

Controls ( )FCHL
Probands ( )All affected ( )

Age (yrs)
Sex (M/F)53/6650/24**111/81*
BMI (Kg/m2)
Current smokers, (%)22 (29.7%)54 (28.1%)
Hypertension, (%)27 (22.7%)14 (18.9%)37 (19.3%)
Blood glucose (mg/dL)
Insulin (mUI/L)
HOMA index
Diabetes, (%)4 (3.4%)2 (2.7%)6 (3.1%)
CAD, (%)11 (14.9%)29 (15.1%)
Plasma lipids (mg/dL)
 TC
 HDL-C
 TG
 LDL-C
 ApoB

Data are reported as means SD.
BMI: body mass index; HOMA: homeostasis model assessment calculated according to Matthews et al. [12]; CAD: coronary artery disease; TC: total cholesterol; HDL-C: high density lipoprotein cholesterol; TG: total triglycerides; LDL-C: low density lipoprotein cholesterol; ApoB: apolipoprotein B; SD: standard deviation; FCHL: familial combined hyperlipidemia; M: male; F: female.
Probands were index cases of each 74 FCHL kindred.
, , and for comparison between controls and probands or all FCHL patients.

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