Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPAR𝜸 Signaling and Inflammation in Murine Mammary Tissue

Figure 1

Hierarchical clustering analysis of DEG (1,496) in mammary tissue from individual lactating mice fed trans-10, cis-12-CLA (CLA) or the control diet (CTR). The colors of the heat map represent the expression of each DEG in mammary tissue versus reference, with red, green, and the various hues denoting greater (red) to lower (green) relative expression (tissue/reference). The average Pearson correlation across animals in the CLA group was 0.38 and for those in the CTR 0.41. The numbers represent an individual mouse within the CLA or CTR group. The clustering by gene is denoted by the pink tree on the left of the figure.