Research Article

Elucidation of the Role of Lectin-Like oxLDL Receptor-1 in the Metabolic Responses of Macrophages to Human oxLDL

Table 3

Metabolic oxygen consumption of various LDL exposure to macrophages. Mean peak MAMP height changes and standard errors for each experimental condition during exposure. All values are calculated based on peak height versus 10 min average basal value prior to exposure. Terms in bold are representative of , indicating statistical significance.

Oxygen
Native LDL (%)Low oxLDL (%)Medium oxLDL (%)High oxLDL (%)Intracel oxLDL (%)

1 µg/ml2.9 ± 0.3611.8 ± 6.30.39 ± 0.7221.7 ± 20.31.6 ± 4.2
p = 0.0013 = 0.1053 = 0.6596 = 0.3639 = 0.7151
10 µg/ml0.3 ± 1.23.47 ± 5.917.1 ± 14.16.27 ± 6.551.0 ± 1.65
= 0.8103 = 0.8338 = 0.2794 = 0.3822 = 0.5915
50 µg/ml1.3 ± 2.212.8 ± 11.222.6 ± 20.72.8 ± 0.788.88 ± 1.47
= 0.583 = 0.3748 = 0.3114p = 0.0161p = 0.0028
100 µg/ml1.7 ± 0.612.1 ± 15.920.7 ± 18.22.36 ± 1.213.14 ± 1.7
p = 0.0371 = 0.5028 = 0.3084 = 0.1594 = 0.1085