The Correlation of Dyslipidemia with the Extent of Coronary Artery Disease in the Multiethnic Study of Atherosclerosis
Table 2
Baseline characteristics and cardiac risk factors of MESA cohort excluding those on lipid-lowering medications and diabetics (collected 2000–2002).
Variable
All
Normal
Combined
HC
MetS
Low HDL
HTG
value
N (%)
4917
2329 (47.4)
172 (3.5)
345 (7.0)
793 (16.1)
907 (18.5)
371 (7.6)
Age (SD)
61.6 (10.3)
62.3 (10.5)
61.9 (9.9)
61.4 (9.5)
60.8 (10.3)
60.8 (10.6)
61.5 (9.4)
0.015
Male gender (%)
2311 (47.0)
1054 (45.3)
74 (43.0)
155 (44.9)
438 (55.2)
406 (44.8)
184 (49.6)
<0.001
Race/ethnicity
<0.001
White (%)
1930 (39.3)
960 (41.2)
70 (40.7)
135 (39.1)
311 (39.2)
282 (31.1)
172 (46.4)
Asian (%)
616 (12.5)
279 (12.0)
20 (11.6)
31 (9.0)
126 (15.9)
117 (12.9)
43 (11.6)
Black (%)
1285 (26.1)
700 (30.1)
24 (14.0)
113 (32.8)
96 (12.1)
303 (33.4)
49 (13.2)
Hispanic (%)
1086 (22.1)
390 (16.8)
58 (33.7)
66 (19.1)
260 (32.8)
205 (22.6)
107 (28.8)
Completed high school (%)
4079 (83.0)
2029 (87.1)
136 (79.1)
285 (82.6)
609 (76.8)
730 (80.5)
290 (78.2)
<0.001
Current smoker (%)
690 (14.0)
296 (12.7)
21 (12.2)
46 (13.3)
143 (18.0)
129 (14.2)
55 (14.8)
0.011
Hypertension (%)
1903 (38.7)
874 (37.5)
62 (36.1)
127 (36.8)
339 (42.8)
336 (37.1)
165 (44.5)
0.014
Waist circumference, cm (SD)
96.8 (14.0)
93.6 (14.4)
100.2 (12.4)
97.0 (12.7)
101.4 (12.6)
99.3 (13.5)
99.0 (13.1)
<0.001
Fasting glucose, mg/dL (SD)
91.1 (19.2)
88.5 (13.6)
95.8 (26.0)
92.0 (21.1)
96.4 (27.9)
91.8 (18.9)
92.0 (19.3)
<0.001
Insulin, mU/L
7.9 (11.4–5.8)
6.7 (9.1–5.0)
9.1 (13.6–6.9)
7.7 (11.0–5.8)
10.9 (14.9–8.0)
9.1 (12.6–6.5)
8.6 (12.5–6.5)
<0.001
CRP, mg/L
1.9 (4.2–0.8)
1.5 (3.7–0.7)
2.4 (5.7–1.2)
1.9 (4.2–1.0)
2.3 (4.4–1.1)
2.2 (4.8–0.9)
2.4 (5.8–1.1)
0.0001
Creatinine, mg/dL (SD)
0.95 (0.22)
0.94 (0.20)
0.94 (0.19)
0.96 (0.19)
0.96 (0.24)
0.94 (0.26)
0.94 (0.23)
0.352
Total cholesterol, mg/dL (SD)
197.1 (35.3)
190.4 (27.1)
262.9 (23.2)
250.0 (22.2)
197.1 (33.4)
175.7 (26.5)
212.0 (30.6)
<0.0001
LDL, mg/dL (SD)
120.4 (31.0)
112.7 (24.4)
177.2 (18.4)
177.2 (18.8)
113.8 (25.7)
114.6 (24.0)
116.3 (25.1)
<0.0001
HDL, mg/dL (SD)
51.5 (15.0)
60.7 (14.2)
44.7 (8.9)
51.9 (11.6)
37.4 (6.0)
40.3 (6.1)
54.2 (10.4)
<0.0001
Triglycerides, mg/dL
108 (156–76)
82 (105–63)
189 (216–171)
106 (126–85)
203 (255–172)
105 (127–83)
185 (221–162)
<0.0001
Median CAC score with range
0 (0–6252)
0 (0–6252)
4.08 (0–2791)
3.74 (0–2348)
0 (0–2946)
0 (0–3358)
0 (0–2867)
<0.001
CAC score > 0(%)
2778 (56.50)
1397 (59.9)
82 (47.6)
161 (46.6)
412 (51.9)
516 (56.8)
210 (56.6)
<0.001
Number of calcified vessels
<0.0001
0 (%)
2778 (56.4)
1397 (59.9)
82 (47.6)
161 (46.6)
412 (51.9)
516 (56.8)
210 (56.6)
1 (%)
889 (18.0)
401 (17.2)
36 (20.9)
79 (22.9)
139 (17.5)
158 (17.4)
76 (20.4)
2 (%)
622 (12.6)
264 (11.3)
18 (10.4)
54 (15.6)
118 (14.8)
131 (14.4)
37 (9.9)
3 (%)
480 (9.7)
204 (8.7)
27 (15.7)
42 (12.1)
89 (32.8)
82 (9.0)
36 (9.7)
4 (%)
148 (3.0)
63 (2.7)
9 (5.2)
9 (2.6)
35 (4.4)
20 (2.2)
12 (3.2)
Multivessel CAC (%)
1250 (25.4)
531 (22.8)
54 (31.4)
105 (30.4)
242 (30.5)
233 (25.6)
85 (22.9)
<0.0001
for categorical variables using Chi-Squared test or for continuous variables using ANOVA. Percentages may not add up to 100% due to rounding. Continuous variables reported using mean (standard deviation) or median (interquartile range). Normal = normolipidemia, Combined = combined hyperlipidemia, HC = hypercholesterolemia, MetS = metabolic syndrome dyslipidemia, and HTG = hypertriglyceridemia.
