Familial Hypercholesterolemia (FH) in Iran: Findings from the Four-Year FH Registry
Table 2
Baseline characteristics of patients with premature coronary heart disease and familial hypercholesterolemia, by Dutch Lipid Clinic Network diagnosis.
Possible ( (86.8%))
Probable ( (8.7%))
Definite ( (4.5%))
Definite and probable ( (13.2%))
Total ()
Demographics
Sex (male)
238 (64.5)
22 (59.5)
8 (42.1)
30 (53.6)
268 (63.1)
Age (years)
Family history of premature CVDa
145 (39.4)
19 (51.4)
11 (57.9)
30 (53.6)
175 (41.3)
Smoking status
Never
248 (67.2)
30 (81.1)
12 (63.2)
42 (75)
290 (68.2)
Current
82 (22.2)
3 (8.1)
3 (15.8)
6 (10.7)
88 (20.7)
Previous
39 (10.6)
4 (10.8)
4 (21.1)
8 (14.3)
47 (11.1)
Presence of Achilles tendon
0 (0)
3 (8.1)
6 (31.6)
9 (16.1)
9 (2.1)
Xanthomas
0 (0)
3 (8.1)
13 (68.4)
16 (28.6)
16 (3.8)
Arcus cornealis
0 (0)
1 (2.7)
0 (0)
1 (1.8)
1 (0.2)
Body mass index (kg/m2)
Comorbidities
Hypertension
242 (65.6)
23 (62.2)
5 (26.3)
28 (50)
270 (63.5)
Diabetes mellitus
101 (27.4)
13 (35.1)
6 (31.6)
19 (33.9)
120 (28.2)
History of CVD
369 (100)
37 (100)
19 (100)
56 (100)
425 (100.0)
Biochemical measures
Total cholesterol (mg/dl)
LDL-cholesterolb (mgr/dl)
HDL-cholesterolc (mgr/dl)
Non-HDL cholesterol (mg/dl)
Triglycerides (mgr/dl)
FBSd
HbA1ce
History of medication use
Lipid-lowering drugs
281 (76.2)
35 (94.6)
15 (78.9)
50 (89.3)
331 (77.9)
Antihypertensive
269 (72.9)
30 (81.1)
8 (42.1)
38 (67.9)
307 (72.2)
Antidiabetics
98 (26.6)
14 (37.8)
5 (26.3)
19 (33.9)
117 (27.5)
Aspirin
242 (65.6)
30 (81.11)
11 (57.9)
41 (73.2)
283 (66.6)
Data are shown as or frequency (percentage). aCVD: cardiovascular disease. bLDL-cholesterol: low-density lipoprotein cholesterol. cHDL-cholesterol: high-density lipoprotein cholesterol. dFBS: fast blood sugar. eHbA1c: hemoglobin A1c.
