Research Article

Sexual Dimorphism and Sex-2D : 4D Interactions on Fasting Lipid Variables in an Adult Ghanaian Population

Table 2

Interactions between sex and the 2D : 4DR on fasting plasma lipid variables.

LR modelDependent variable95% CI value
LowerUpper

1TCHOL (mmol/L)
(Constant)4.9322.7977.068<0.001
Age (years)0.061-0.0210.1430.141
BMI (kg/m2)-0.071-0.136-0.0060.033
Sex-0.040-0.4660.3870.854
2D : 4DR7.379-0.53015.2880.067
-9.392-20.0551.2700.084

2TRIG (mmol/L)
(Constant)1.001-0.1692.1720.093
Age0.012-0.0320.0570.589
BMI-0.004-0.0400.0330.836
Sex0.092-0.1390.3240.431
2D : 4DR1.680-2.7356.0950.452
-0.586-6.4695.2970.844

3HDL-C (mmol/L)
(Constant)2.2710.9463.5960.001
Age (years)0.038-0.0130.0890.143
BMI (kg/m2)-0.057-0.098-0.0170.006
Sex-0.136-0.4000.1290.311
2D : 4DR6.1771.26911.0850.014
-10.480-17.097-3.8640.002

4LDL-C (mmol/L)
(Constant)2.1010.4123.7890.015
Age (years)0.017-0.0480.0810.609
BMI (kg/m2)-0.006-0.0590.0470.820
Sex0.049-0.2860.3830.773
2D : 4DR-0.384-6.7555.9870.905
2.116-6.37310.6060.622

5VLDL-C (mmol/L)
(Constant)0.456-0.0760.9880.092
Age (years)0.006-0.0150.0260.589
BMI (kg/m2)-0.002-0.0180.0150.831
Sex0.042-0.0630.1480.429
2D : 4DR0.793-1.2162.8010.435
-0.288-2.9642.3880.831

6CR
(Constant)1.175-3.3705.7190.609
Age (years)0.025-0.1500.1990.780
BMI (kg/m2)0.095-0.0440.2330.180
Sex0.594-0.3131.5020.197
2D : 4DR-3.882-20.71112.9480.648
17.062-5.62739.7510.139

The 2D : 4DR was centered before linear regression (LR) analysis. TCHOL: total cholesterol; TRIG: triglycerides; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein; VLDL: very low-density lipoprotein; C: cholesterol; CR: coronary risk; BMI: body mass index.