Research Article
Impact of Alexithymia on the Lipid Profile in Major Depressed Individuals
| | Variables | Depression without dyslipidaemia | Depression with dyslipidaemia | OR (CI 95%) | value |
| | Gender | | | | 0.201 | | Female | 59.7% | 40.3% | 1 | | Male | 51.5% | 48.5% | 1.40 (0.84 to 2.34) | | BMI (kg/m2) | | | | <0.001 | | <25 | 74.7% | 25.3% | 1 | | ≥25 & <30 | 49.4% | 50.6% | 3.02 (1.54 to 5.89) | | ≥30 | 46.3% | 53.7% | 3.43 (1.73 to 6.77) | | Age (years) | | | | 0.206 | | <50 | 59.1% | 40.9% | 1 | | ≥50 | 50.6% | 49.4% | 1.41 (0.83 to 2.41) | | Benzodiazepine receptor agonists | | | | 0.347 | | No | 57.6% | 42.4% | 1 | | Yes | 50.0% | 50.0% | 1.36 (0.72 to 2.59) | | Antidepressant therapy | | | | 0.774 | | No | 55.6% | 44.4% | 1 | | Yes | 57.5% | 42.5% | 0.92 (0.54 to 1.59) | | Other psychotropic treatments | | | | 0.655 | | No | 56.7% | 43.3% | 1 | | Yes | 52.0% | 48.0% | 1.21 (0.53 to 2.79) | | Smoking | | | | 0.105 | | No | 58.8% | 41.2% | 1 | | Yes | 46.0% | 54.0% | 1.68 (0.90 to 3.14) | | Alcohol | | | | 0.913 | | No | 55.0% | 45.0% | 1 | | Occasional | 57.5% | 42.5% | 0.90 (0.52 to 1.56) | | Regular | 58.3% | 41.7% | 0.87 (0.36 to 2.10) | | Caffeine | | | | 0.356 | | No | 63.6% | 36.4% | 1 | | Yes | 55.0% | 45.0% | 1.43 (0.67 to 3.06) | | Snoring | | | | 0.001 | | No | 70.1% | 29.9% | 1 | | Yes | 48.4% | 51.6% | 2.50 (1.43 to 4.37) | | OSAS | | | | 0.001 | | No | 65.2% | 34.8% | 1 | | Yes | 43.6% | 56.4% | 2.43 (1.44 to 4.11) | | Insomnia disorders | | | | 0.652 | | No | 51.1% | 48.9% | 1 | | Sleep deprivation alone | 51.8% | 48.2% | 0.97 (0.37 to 2.52) | | With | 60.2% | 39.8% | 0.69 (0.35 to 1.38) | | With | 53.2% | 46.8% | 0.92 (0.41 to 2.09) | | Sleep movement disorders | | | | 0.631 | | No | 57.9% | 42.1% | 1 | | Moderate to severe PLMs | 51.6% | 48.4% | 1.29 (0.60 to 2.77) | | RLS alone or combined with PLMs | 50.0% | 50.0% | 1.38 (0.62 to 3.05) | | Excessive daytime sleepiness | | | | 0.230 | | No | 60.4% | 39.6% | 1 | | Yes | 52.7% | 47.3% | 1.37 (0.82 to 2.28) | | Depression severity | | | | 0.110 | | Mild | 64.1% | 35.9% | 1 | | Moderate | 49.1% | 50.9% | 1.85 (1.02 to 3.36) | | Severe | 59.3% | 40.7% | 1.23 (0.60 to 2.51) | | Hypertension | | | | 0.002 | | No | 64.0% | 36.0% | 1 | | Yes | 43.5% | 56.5% | 2.31 (1.36 to 3.93) | | Type 2 diabetes | | | | <0.001 | | No | 62.1% | 37.9% | 1 | | Yes | 16.1% | 83.9% | 8.51 (3.14 to 23.07) | | CRP | | | | 0.011 | | <1 | 69.5% | 30.5% | 1 | | ≥1 & <3 | 47.5% | 52.5% | 2.52 (1.32 to 4.79) | | ≥3 | 51.2% | 48.9% | 2.17 (1.14 to 4.12) | | Alexithymia | | | | 0.013 | | No | 65.4% | 34.6% | 1 | | Yes | 49.3% | 50.7% | 1.94 (1.15 to 3.28) |
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BMI = body mass index; OSAS = obstructive sleep apnoea syndrome; CRP = C-reactive protein; PLMs = periodic limb movements during sleep; RLS = restless legs syndrome.
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