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Journal of Nucleic Acids
Volume 2010, Article ID 632041, 9 pages
http://dx.doi.org/10.4061/2010/632041
Research Article

Development of a Novel Fluorescence Assay Based on the Use of the Thrombin-Binding Aptamer for the Detection of -Alkylguanine-DNA Alkyltransferase Activity

1Institute for Research in Biomedicine (IRB Barcelona) IQAC-CSIC, CIBER-BBN Networking Centre on Bioengineering Biomaterials and Nanomedicine, Cluster Building, Baldiri i Reixac 10, 08028 Barcelona, Spain
2Chemical and Physical Biology CIB (CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain

Received 11 June 2010; Accepted 17 July 2010

Academic Editor: Ashis Basu

Copyright © 2010 Maria Tintoré et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [12 citations]

The following is the list of published articles that have cited the current article.

  • Anna Avino, Carme Fabrega, Maria Tintore, and Ramon Eritja, “Thrombin Binding Aptamer, More than a Simple Aptamer: Chemically Modified Derivatives and Biomedical Applications,” Current Pharmaceutical Design, vol. 18, no. 14, pp. 2036–2047, 2012. View at Publisher · View at Google Scholar
  • Giuseppe Perugino, Antonella Vettone, Giuseppina Illiano, Anna Valenti, Maria C. Ferrara, Mose Rossi, and Maria Ciaramella, “Activity and Regulation of Archaeal DNA Alkyltransferase CONSERVED PROTEIN INVOLVED IN REPAIR OF DNA ALKYLATION DAMAGE,” Journal Of Biological Chemistry, vol. 287, no. 6, pp. 4222–4231, 2012. View at Publisher · View at Google Scholar
  • Osman Doluca, Jamie M. Withers, and Vyacheslav V. Filichev, “Molecular Engineering of Guanine-Rich Sequences: Z-DNA, DNA Triplexes, and G-Quadruplexes,” Chemical Reviews, vol. 113, no. 5, pp. 3044–3083, 2013. View at Publisher · View at Google Scholar
  • Isaac Gallego, Brendan Manning, Ramon Eritja, and Maria Tintore, “DNA Origami as a DNA Repair Nanosensor at the Single-Molecule Level,” Angewandte Chemie-International Edition, vol. 52, no. 30, pp. 7747–7750, 2013. View at Publisher · View at Google Scholar
  • Maria Tintoré, Ramon Eritja, and Carmen Fábrega, “DNA Nanoarchitectures: Steps towards Biological Applications,” ChemBioChem, 2014. View at Publisher · View at Google Scholar
  • Maria Tintoré, Santiago Grijalvo, Ramon Eritja, and Carme Fàbrega, “Synthesis of oligonucleotides carrying fluorescently labelled O6-alkylguanine for measuring hAGT activity,” Bioorganic & Medicinal Chemistry Letters, 2015. View at Publisher · View at Google Scholar
  • Maria Tintoré, Stefania Mazzini, Laura Polito, Marcello Marelli, Alfonso Latorre, Álvaro Somoza, Anna Aviñó, Carme Fàbrega, and Ramon Eritja, “Gold-Coated Superparamagnetic Nanoparticles for Single Methyl Discrimination in DNA Aptamers,” International Journal of Molecular Sciences, vol. 16, no. 11, pp. 27625–27639, 2015. View at Publisher · View at Google Scholar
  • Andrew A. Beharry, Zachary D. Nagel, Leona D. Samson, and Eric T. Kool, “Fluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug Response,” Plos One, vol. 11, no. 4, 2016. View at Publisher · View at Google Scholar
  • Riccardo Miggiano, Anna Valenti, Franca Rossi, Menico Rizzi, Giuseppe Perugino, and Maria Ciaramella, “Every OGT Is Illuminated … by Fluorescent and Synchrotron Lights,” International Journal of Molecular Sciences, vol. 18, no. 12, pp. 2613, 2017. View at Publisher · View at Google Scholar
  • Yuezhou Zhang, Jing Tu, Dongqing Wang, Haitao Zhu, Sajal Kumar Maity, Xiangmeng Qu, Bram Bogaert, Hao Pei, and Hongbo Zhang, “Programmable and Multifunctional DNA-Based Materials for Biomedical Applications,” Advanced Materials, pp. 1703658, 2018. View at Publisher · View at Google Scholar
  • Ramon Eritja, Anna Aviñó, Carme Fàbrega, Adele Alagia, Andreia F. Jorge, and Santiago Grijalvo, “Synthesis of Oligonucleotides Carrying Nucleic Acid Derivatives of Biomedical and Structural Interest,” Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives, pp. 237–258, 2018. View at Publisher · View at Google Scholar
  • Shih-Han Hsu, Shang-Hung Chen, Ching-Chuan Kuo, and Jang-Yang Chang, “Ubiquitin-conjugating enzyme E2 B regulates the ubiquitination of O-methylguanine-DNA methyltransferase and BCNU sensitivity in human nasopharyngeal carcinoma cells,” Biochemical Pharmacology, 2018. View at Publisher · View at Google Scholar