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Journal of Nucleic Acids
Volume 2011 (2011), Article ID 896947, 14 pages
http://dx.doi.org/10.4061/2011/896947
Research Article

Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA

1The Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 987696 Nebraska Medical Center, Omaha, NE 68198-7696, USA
2Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198-6025, USA

Received 15 December 2010; Accepted 11 March 2011

Academic Editor: Shigenori Iwai

Copyright © 2011 Aishwarya Prakash et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary Figure S1: SDS-PAGE stained with Coomassie Blue after protein purification.

Supplementary Figure S2: Circular dichroism spectra of proteins alone at varying temperatures.

Supplementary Figure S3: Proteins bind specifically to ssDNA.

Supplementary Figure S4: Abundance of trinucleotides from SELEX with RPACDE.

Supplementary Figure S5: TC23 and binding to protein constructs.

Supplementary Figure S6: Characterizaion of RPA-CDE binding to Gq23.

  1. Supplementary Figures