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Journal of Nucleic Acids
Volume 2012, Article ID 591025, 9 pages
http://dx.doi.org/10.1155/2012/591025
Research Article

Inhibition of HIV Replication by Cyclic and Hairpin PNAs Targeting the HIV-1 TAR RNA Loop

1Institut de Chimie de Nice, UMR CNRS 7272, Université de Nice-Sophia Antipolis, 28 Avenue de Valrose, F06100 Nice, France
2Department of Biochemistry and Molecular Biology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, Newark, NJ 07103, USA

Received 30 May 2012; Accepted 12 July 2012

Academic Editor: Eriks Rozners

Copyright © 2012 Gregory Upert et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supporting Information Available: A) HPLC and ESI MS spectra of PNA 3-6 and TPP-[PNA 1a-c, 2-6] conjugates (p. S2-S13). B) UV-monitored thermal denaturation: First-derivative melting curves of PAA 4-6 and PAA 4-6/TAR complexes (p. S14).

  1. Supplementary Material