Research Article

Overexpression of PCNA Attenuates Oxidative Stress-Caused Delay of Gap-Filling during Repair of UV-Induced DNA Damage

Figure 4

The effect of PCNA knockdown on gap-filling during repair of UV-induced DNA lesions. Similar to the procedures described in Figure 1, yet colcemid was excluded to avoid “overdelay.” AGS cells were stably transfected with pLKO-1 shPCNA to knock down PCNA (closed circles) or control vector (open circles).