Research Article

On the Complexity of Electrostatic Suspension Stabilization of Functionalized Silica Nanoparticles for Biotargeting and Imaging Applications

Table 1

IEP values for protein-conjugated particles as determined from electrokinetic titrations in water or in saline solution (SS) with the same ionic strength as used in biological media (0.154 M).

GlutaraldehydeSuccinic acidPEI

Stv-Alexa555, in water6.15.99.3
Stv-Alexa555, in SS7.16.28.2
Stv 30 μg (unlabeled) in SS8.56.210.2
Stv-DyLight549, in water7.9
Stv-DyLight549, in SS6.8