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Journal of Nanomaterials
Volume 2009, Article ID 498505, 6 pages
Research Article

Synthesis and Antimicrobial Activity of a Silver-Hydroxyapatite Nanocomposite

1Department of Biomaterials and Bioinspired Materials, Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Cantoblanco, 28049, Madrid, Spain
2Department of Ceramic, Instituto de Cerámica y Vidrio (ICV-CSIC), Cantoblanco, 28049, Madrid, Spain
3Department of Nanostructured Materials, Centro de Investigación en Nanomateriales y Nanotecnología (CINN-CSIC), Francisco Pintado Fe 26, 33011, Oviedo, Spain
4Instituto de Cerámica de Galicia, Universidad de Santiago de Compostela, 15706, Santiago de Compostela, Spain

Received 21 August 2008; Revised 14 January 2009; Accepted 13 March 2009

Academic Editor: Maryam Tabrizian

Copyright © 2009 Marcos Díaz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles ( 65 nm) supported onto the HA particles ( 130 nm) surface without a high degree of agglomeration. The bactericidal effect against common Gram-positive and Gram-negative bacteria has been also investigated. The results indicated a high antimicrobial activity for Staphylococcus aureus, Pneumococcus and Escherichia coli, so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery applications.