Nanoencapsulation of Nimodipine in Novel Biocompatible Poly(propylene-co-butylene succinate) Aliphatic Copolyesters for Sustained Release

Table 3

Nanoparticle Yield, drug loading, entrapment efficiency and mean diameter of Nimodipine loaded PPBSu nanoparticles.

Sample	Drug Loading (%)	Entrapment Efficiency (%)	Micelle Yield (%)	Mean Diameter (nm)	PdI*
PPBSu 100/0	8.43	72.9	75.77±4.92	191.5±13.43	0.167
PPBSu 90/10	9.07	85.0	75.44±6.39	180.5±7.78	0.174
PPBSu 80/20	9.05	83.0	78.95±1.61	190±4.24	0.112
PPBSu 70/30	8.56	73.6	78.78±0.62	210±5.66	0.179
PPBSu 60/40	8.75	72.7	77.44±2.57	182.5±10.61	0.132
PPBSu 50/50	8.09	69.7	76.91±2.11	210.5±0.71	0.140

∗PdI: Polydispersity Index.