Research Article

Controlled Release of Doxorubicin from Doxorubicin/-Polyglutamic Acid Ionic Complex

Table 1

Complexation efficiencies for DOX/ 𝛾 -PGA complexes formed by mixing DOX and PGA in different weight ratios ( 𝑛 = 3).

DOX :  𝛾 -PGA ratio (w/w)Complexation efficiency (%)Aqueous solubility

1 : 10099 ± 0.89Soluble
1 : 5099.3 ± 1.2Soluble
1 : 1099.7 ± 2.65Soluble
1 : 199.1 ± 0.6Precipitate
2 : 195.4 ± 4.1Precipitate
3 : 196 ± 6.5Precipitate