Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications
Figure 5
TEM images of immortalized progenitor cells 6 h after incubation with (a) silica-, (b) APTMS- and (c) AEAPTMS-coated USPIO particles at an iron concentration of 0.3 mol/mL. The particles were located intracellularly and most of them were aggregated in large lysosomes. Image (d) shows the process of USPIO nanoparticle uptake into the cells. (Reprinted with permission from [48]).