Review Article

Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications

Figure 5

TEM images of immortalized progenitor cells 6 h after incubation with (a) silica-, (b) APTMS- and (c) AEAPTMS-coated USPIO particles at an iron concentration of 0.3  𝜇 mol/mL. The particles were located intracellularly and most of them were aggregated in large lysosomes. Image (d) shows the process of USPIO nanoparticle uptake into the cells. (Reprinted with permission from [48]).
894303.fig.005a
(a)
894303.fig.005b
(b)
894303.fig.005c
(c)
894303.fig.005d
(d)