Advanced Nanomaterials in Multimodal Imaging: Design, Functionalization, and Biomedical Applications

Figure 7

Cartoon for cytosolic delivery process of polymeric nanoparticles (NPs). (a) Cellular internalization of NPs; (b) Formation of lysosome-NPs by endocytosis; (c) Release of therapeutic agents in cytoplasm; (d) Degradation of agents; (e) Exocytosis of NPs; (f) Cytosolic transport of agents to targets.