Review Article

Gold Nanoparticles: Promising Nanomaterials for the Diagnosis of Cancer and HIV/AIDS

Figure 7

Breath testing as a method for detecting lung cancer. (a) (i) Array of chemiresistors, (ii) image of chemiresistor using scanning electron microscope (SEM), (iii) image of AuNPs film located between two adjacent electrodes using SEM, and (iv) transmission electron microscope (TEM) image of monolayer-capped AuNPs appearing as dark dots and the capping organic molecules as bright medium between the adjacent dots. The AuNPs in the films provide the necessary electrical conductivity, and the organic film component provides sites for the sorption of analyte molecules. (b) The exhaled breath (from patients) and simulated breath (mixture of representative VOCs at concentrations similar to those determined by GC-MS analysis of exhaled patient’s breath) using the array of AuNPs sensors. (Reprinted with permission from Nature Publishing Group, [71]).
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