Development of Quantitative Structure-Property Relationship Models for Self-Emulsifying Drug Delivery System of 2-Aryl Propionic Acid NSAIDs

Table 2

Values of important descriptors.

Component	Dipole	MaxQ^−	MaxQ^+	ABSQ	ELUMO	EHOMO	LogD	Volume	Wiener index
Ketoprofen	4.6178	−0.1264	0.7765	9.4418	0.07479	−0.33786	1.906	167.38	724
Ibuprofen	1.9316	−0.0067	0.7825	8.4045	0.13177	−0.32242	2.150	152.63	404
Flurbiprofen	3.2118	−0.0234	0.7838	8.3569	0.09569	−0.28772	1.394	155.37	530
Naproxen	0.3521	−0.7313	0.7820	8.2233	0.09868	−0.31306	3.748	155.72	626
Loxoprofen	1.7058	−0.3306	0.3272	3.6074	0.27676	−0.27805	3.003	168.75	672
Carprofen	4.7591	−1.0815	0.7836	9.0201	0.08655	−0.29753	2.233	178.7	689
Tween HS	7.0424	−0.5202	0.6213	38.9571	0.17706	−0.40723	−4.492	749.79	44308
Tween20Ls	0.0547	−0.2885	0.1508	7.0901	0.22476	−0.41273	5.389	137.54	220
Tween40Ls	0.0546	−0.2885	0.1507	9.4410	0.22384	−0.40605	7.214	183.5	560
Tween80Ls	0.2610	−0.1646	0.1666	10.3074	0.18531	−0.33536	7.682	209.91	816
Oleic acid	2.0597	−0.1638	0.7540	12.8007	0.16604	−0.33764	5.412	231.18	1313
Ethyl oleate	2.2099	−0.1640	0.7924	13.7649	0.17516	−0.33703	7.435	257.24	1720
IPM	2.2730	−0.2715	0.8086	12.7784	0.17604	−0.40761	6.432	227.4	1072
Methyl laurate	2.3148	−0.1217	0.7871	9.8417	0.17346	−0.4139	4.793	173.9	538
Methyl oleate	2.0349	−0.1218	0.7872	13.0583	0.17314	−0.33705	7.086	243.18	1506
Butyl oleate	2.2902	−0.1522	0.7658	14.935	0.17492	−0.33731	8.415	279.88	2215
Ethanol	2.1046	−0.4459	0.4001	2.4001	0.22361	−0.43772	−0.010	38.75	4
1, 2-propanol	3.1810	−0.4491	0.4246	3.9863	0.2109	−0.42825	−0.520	54.87	18
Ethylene glycol monoethyl ether	0.4875	−0.4526	0.4074	3.9245	0.21824	−0.4152	−0.141	67.91	35
n-Butanol	2.0417	−0.2890	0.3996	3.6342	0.22567	−0.43685	0.970	60.36	20
Isopropyl alcohol	2.0903	−0.4291	0.3965	3.2827	0.21465	−0.43207	0.368	49.39	9
Diethylene glycol monoethyl ether	2.0613	−0.4526	0.4079	5.4420	0.21531	−0.41581	−0.272	98.09	120