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Journal of Nanomaterials
Volume 2011, Article ID 291512, 6 pages
http://dx.doi.org/10.1155/2011/291512
Research Article

Characterization of Sucrose Thin Films for Biomedical Applications

1Department of Multifunctional Nanoparticles for Biomedical Applications, National Institute of Materials Physics, P.O. Box MG7, Magurele, 077125 Bucharest, Romania
2Department of Biochemistry and Molecular Biology, University of Bucharest, 050095 Bucharest, Romania

Received 29 July 2010; Accepted 8 February 2011

Academic Editor: Kui Yu

Copyright © 2011 S. L. Iconaru et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Sucrose is a natural osmolyte accumulated in the cells of organisms as they adapt to environmental stress. In vitro sucrose increases protein stability and forces partially unfolded structures to refold. Thin films of sucrose (C12H22O11) were deposited on thin cut glass substrates by the thermal evaporation technique ( torr). Characteristics of thin films were put into evidence by Fourier Transform Infrared Spectroscopy (FTIR), X-ray Photoelectron Spectroscopy (XPS), scanning electron microscopy (SEM), and differential thermal analysis and thermal gravimetric analysis (TG/DTA). The experimental results confirm a uniform deposition of an adherent layer. In this paper we present a part of the characteristics of sucrose thin films deposited on glass in medium vacuum conditions, as a part of a culture medium for osteoblast cells. Osteoblast cells were used to determine proliferation, viability, and cytotoxicity interactions with sucrose powder and sucrose thin films. The osteoblast cells have been provided from the American Type Culture Collection (ATCC) Centre. The outcome of this study demonstrated the effectiveness of sucrose thin films as a possible nontoxic agent for biomedical applications.