Optimization of the Preparation Process for an Oral Phytantriol-Based Amphotericin B Cubosomes

Figure 1

Particle size distribution of cubosome dispersion measured for three times via Zetasizer Nano ZS90. Homogenization conditions: (a) ultrasound only; (b) 600 bar for 3 cycles; (c) 600 bar for 9 cycles; (d) 1200 bar for 6 cycles; (e) 1200 bar for 9 cycles; (f) 1800 bar for 9 cycles.

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