Optimization of the Preparation Process for an Oral Phytantriol-Based Amphotericin B Cubosomes

Figure 2

SAXS profiles of the cubic liquid-crystalline structure: (a) phytantriol-based cubosome dispersions homogenized at 1200 bar for 9 cycles; (b) at 1800 bar for 9 cycles; (c) phytantriol-based cubosomes containing AmB homogenized at 1200 bar for 9 cycles; (d) the bulk cubic phase with melts of phytantriol and Poloxamer 407 at a ratio of 9 : 1.