Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2011, Article ID 391596, 5 pages
Research Article

Mechanical Properties of Chitosan-Starch Composite Filled Hydroxyapatite Micro- and Nanopowders

1School of Advanced Medical Technologies, Tehran University of Medical Sciences, Tehran, Iran
2Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshty University of Medical Sciences, Tehran, Iran
3Department of Biomaterials Engineering, Tonekabon Branch, Islamic Azad University, Tonekabon, Iran

Received 30 April 2011; Revised 4 July 2011; Accepted 4 July 2011

Academic Editor: Donglu Shi

Copyright © 2011 Jafar Ai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Hydroxyapatite is a biocompatible ceramic and reinforcing material for bone implantations. In this study, Starch-chitosan hydrogel was produced using the oxidation of starch solution and subsequently cross-linked with chitosan via reductive alkylation method (weight ratio (starch/chitosan): 0.38). The hydroxyapatite micropowders and nanopowders synthesized by sol-gel method (10, 20, 30, 40 %W) were composited to hydrogels and were investigated by mechanical analysis. The results of SEM images and Zetasizer experiments for synthesized nanopowders showed an average size of 100 nm. The nanoparticles distributed as uniform in the chitosan-starch film. The tensile modulus increased for composites containing hydroxyapatite nano-(size particle: 100 nanometer) powders than composites containing micro-(size particle: 100 micrometer) powders. The swelling percentage decreased for samples containing hydroxyapatite nanopowder than the micropowders. These nanocomposites could be applied for hard-tissue engineering.