Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2011, Article ID 407402, 6 pages
http://dx.doi.org/10.1155/2011/407402
Review Article

Facilitating Effects of Nanoparticles/Materials on Sensitive Immune-Related Lung Disorders

1Department of Public Health and Molecular Toxicology, School of Pharmacy Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
2Environmental Health Sciences Division, National Institute for Environmental Studies, Tsukuba, Ibaraki 305-8506, Japan

Received 8 June 2010; Accepted 5 July 2010

Academic Editor: Hugh D. Smyth

Copyright © 2011 Ken-ichiro Inoue and Hirohisa Takano. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. M. Samet, F. Dominici, F. C. Curriero, I. Coursac, and S. L. Zeger, “Fine particulate air pollution and mortality in 20 U.S. cities, 1987–1994,” New England Journal of Medicine, vol. 343, no. 24, pp. 1742–1749, 2000. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Peters, H. E. Wichmann, T. Tuch, J. Heinrich, and J. Heyder, “Respiratory effects are associated with the number of ultrafine particles,” American Journal of Respiratory and Critical Care Medicine, vol. 155, no. 4, pp. 1376–1383, 1997. View at Google Scholar · View at Scopus
  3. M. Szyszkowicz, “Air pollution and emergency department visits for depression in Edmonton, Canada,” International Journal of Occupational Medicine and Environmental Health, vol. 20, no. 3, pp. 241–245, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. N. Künzli, P.-O. Bridevaux, L.-J. S. Liu et al., “Traffic-related air pollution correlates with adult-onset asthma among never-smokers,” Thorax, vol. 64, no. 8, pp. 664–670, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. B. Neupane, M. Jerrett, R. T. Burnett, T. Marrie, A. Arain, and M. Loeb, “Long-term exposure to ambient air pollution and risk of hospitalization with community-acquired pneumonia in older adults,” American Journal of Respiratory and Critical Care Medicine, vol. 181, no. 1, pp. 47–53, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. D. W. Dockery, C. A. Pope III, X. Xu et al., “An association between air pollution and mortality in six U.S. cities,” New England Journal of Medicine, vol. 329, no. 24, pp. 1753–1759, 1993. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Nemmar, S. Al-Salam, S. Zia, J. Yasin, I. Al Husseni, and B. H. Ali, “Diesel exhaust particles in the lung aggravate experimental acute renal failure,” Toxicological Sciences, vol. 113, no. 1, pp. 267–277, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. F. D. T. Q. S. Lopes, T. S. Pinto, F. M. Arantes-Costa et al., “Exposure to ambient levels of particles emitted by traffic worsens emphysema in mice,” Environmental Research, vol. 109, no. 5, pp. 544–551, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. K.-I. Inoue, H. Takano, R. Yanagisawa, T. Ichinose, A. Shimada, and T. Yoshikawa, “Pulmonary exposure to diesel exhaust particles induces airway inflammation and cytokine expression in NC/Nga mice,” Archives of Toxicology, vol. 79, no. 10, pp. 595–599, 2005. View at Publisher · View at Google Scholar · View at Scopus
  10. T. Ichinose, A. Furuyama, and M. Sagai, “Biological effects of diesel exhaust particles (DEP). II. Acute toxicity of DEP introduced into lung by intratracheal instillation,” Toxicology, vol. 99, no. 3, pp. 153–167, 1995. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Ichinose, Y. Yajima, M. Nagashima, S. Takenoshita, Y. Nagamachi, and M. Sagai, “Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles,” Carcinogenesis, vol. 18, no. 1, pp. 185–192, 1997. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Takano, T. Yoshikawa, T. Ichinose, Y. Miyabara, K. Imaoka, and M. Sagai, “Diesel exhaust particles enhance antigen-induced airway inflammation and local cytokine expression in mice,” American Journal of Respiratory and Critical Care Medicine, vol. 156, no. 1, pp. 36–42, 1997. View at Google Scholar · View at Scopus
  13. H. Takano, R. Yanagisawa, T. Ichinose et al., “Diesel exhaust particles enhance lung injury related to bacterial endotoxin through expression of proinflammatory cytokines, chemokines, and intercellular adhesion molecule-1,” American Journal of Respiratory and Critical Care Medicine, vol. 165, no. 9, pp. 1329–1335, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. K.-I. Inoue, H. Takano, M. Sakurai et al., “Pulmonary exposure to diesel exhaust particles enhances coagulatory disturbance with endothelial damage and systemic inflammation related to lung inflammation,” Experimental Biology and Medicine, vol. 231, no. 10, pp. 1626–1632, 2006. View at Google Scholar · View at Scopus
  15. K.-I. Inoue, E. Koike, H. Takano, R. Yanagisawa, T. Ichinose, and T. Yoshikawa, “Effects of diesel exhaust particles on antigen-presenting cells and antigen-specific Th immunity in mice,” Experimental Biology and Medicine, vol. 234, no. 2, pp. 200–209, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Cyrys, M. Stölzel, J. Heinrich et al., “Elemental composition and sources of fine and ultrafine ambient particles in Erfurt, Germany,” Science of the Total Environment, vol. 305, no. 1–3, pp. 143–156, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. K. L. Timonen, G. Hoek, J. Heinrich et al., “Daily variation in fine and ultrafine particulate air pollution and urinary concentrations of lung Clara cell protein CC16,” Occupational and Environmental Medicine, vol. 61, no. 11, pp. 908–914, 2004. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Zhu, W. C. Hinds, S. Kim, and C. Sioutas, “Concentration and size distribution of ultrafine particles near a major highway,” Journal of the Air and Waste Management Association, vol. 52, no. 9, pp. 1032–1042, 2002. View at Google Scholar · View at Scopus
  19. M. J. Utell and M. W. Frampton, “Acute health effects of ambient air pollution: the ultrafine particle hypothesis,” Journal of Aerosol Medicine, vol. 13, no. 4, pp. 355–359, 2000. View at Google Scholar · View at Scopus
  20. G. Oberdörster, “Pulmonary effects of inhaled ultrafine particles,” International Archives of Occupational and Environmental Health, vol. 74, no. 1, pp. 1–8, 2001. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Seaton, W. MacNee, K. Donaldson, and D. Godden, “Particulate air pollution and acute health effects,” Lancet, vol. 345, no. 8943, pp. 176–178, 1995. View at Google Scholar · View at Scopus
  22. D. M. Brown, M. R. Wilson, W. MacNee, V. Stone, and K. Donaldson, “Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines,” Toxicology and Applied Pharmacology, vol. 175, no. 3, pp. 191–199, 2001. View at Publisher · View at Google Scholar · View at Scopus
  23. C. A. J. Dick, D. M. Brown, K. Donaldson, and V. Stone, “The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types,” Inhalation Toxicology, vol. 15, no. 1, pp. 39–52, 2003. View at Publisher · View at Google Scholar · View at Scopus
  24. N. Li, C. Sioutas, A. Cho et al., “Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage,” Environmental Health Perspectives, vol. 111, no. 4, pp. 455–460, 2003. View at Google Scholar · View at Scopus
  25. R. F. Service, “Nanotechnology grows up,” Science, vol. 304, no. 5678, pp. 1732–1734, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. H. Gong Jr., W. S. Linn, K. W. Clark et al., “Exposures of healthy and asthmatic volunteers to concentrated ambient ultrafine particles in Los Angeles,” Inhalation Toxicology, vol. 20, no. 6, pp. 533–545, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. M. W. Frampton, J. C. Stewart, G. Oberdörster et al., “Inhalation of ultrafine particles alters blood leukocyte expression of adhesion molecules in humans,” Environmental Health Perspectives, vol. 114, no. 1, pp. 51–58, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. M. P. Vincenti, T. A. Burrell, and S. M. Taffet, “Regulation of NF-κB activity in murine macrophages: effect of bacterial lipopolysaccharide and phorbol ester,” Journal of Cellular Physiology, vol. 150, no. 1, pp. 204–213, 1992. View at Google Scholar · View at Scopus
  29. T. R. Ulich, L. R. Watson, S. Yin et al., “The intratracheal administration of endotoxin and cytokines: I. Characterization of LPS-induced IL-1 and TNF mRNA expression and the LPS-, IL-1-, and TNF-induced inflammatory infiltrate,” American Journal of Pathology, vol. 138, no. 6, pp. 1485–1496, 1991. View at Google Scholar · View at Scopus
  30. P. G. Flanagan, S. K. Jackson, and G. Findlay, “Diagnosis of gram negative, ventilator associated pneumonia by assaying endotoxin in bronchial lavage fluid,” Journal of Clinical Pathology, vol. 54, no. 2, pp. 107–110, 2001. View at Publisher · View at Google Scholar · View at Scopus
  31. T. R. Martin, G. D. Rubenfeld, J. T. Ruzinski et al., “Relationship between soluble CD14, lipopolysaccharide binding protein, and the alveolar inflammatory response in patients with acute respiratory distress syndrome,” American Journal of Respiratory and Critical Care Medicine, vol. 155, no. 3, pp. 937–944, 1997. View at Google Scholar · View at Scopus
  32. S. Becker, M. J. Fenton, and J. M. Soukup, “Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles,” American Journal of Respiratory Cell and Molecular Biology, vol. 27, no. 5, pp. 611–618, 2002. View at Google Scholar · View at Scopus
  33. R. Yanagisawa, H. Takano, K. Inoue et al., “Enhancement of acute lung injury related to bacterial endotoxin by components of diesel exhaust particles,” Thorax, vol. 58, no. 7, pp. 605–612, 2003. View at Publisher · View at Google Scholar · View at Scopus
  34. K.-I. Inoue, H. Takano, R. Yanagisawa et al., “Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice,” Environmental Health Perspectives, vol. 114, no. 9, pp. 1325–1330, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. K.-I. Inoue, H. Takano, M. Ohnuki et al., “Size effects of nanomaterials on lung inflammation and coagulatory disturbance,” International Journal of Immunopathology and Pharmacology, vol. 21, no. 1, pp. 197–206, 2008. View at Google Scholar · View at Scopus
  36. K.-I. Inoue, H. Takano, R. Yanagisawa, E. Koike, and A. Shimada, “Size effects of latex nanomaterials on lung inflammation in mice,” Toxicology and Applied Pharmacology, vol. 234, no. 1, pp. 68–76, 2009. View at Publisher · View at Google Scholar · View at Scopus
  37. K.-I. Inoue, H. Takano, E. Koike et al., “Effects of pulmonary exposure to carbon nanotubes on lung and systemic inflammation with coagulatory disturbance induced by lipopolysaccharide in mice,” Experimental Biology and Medicine, vol. 233, no. 12, pp. 1583–1590, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. K.-I. Inoue, H. Takano, R. Yanagisawa et al., “Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice,” Toxicology, vol. 238, no. 2-3, pp. 99–110, 2007. View at Publisher · View at Google Scholar · View at Scopus
  39. D. K. Agrawal and Z. Shao, “Pathogenesis of allergic airway inflammation,” Current Allergy and Asthma Reports, vol. 10, no. 1, pp. 39–48, 2010. View at Google Scholar
  40. K. Maejima, K. Tamura, Y. Taniguchi, S. Nagase, and H. Tanaka, “Comparison of the effects of various fine particles on IgE antibody production in mice inhaling Japanese cedar pollen allergens,” Journal of Toxicology and Environmental Health, Part A, vol. 52, no. 3, pp. 231–248, 1997. View at Google Scholar · View at Scopus
  41. A. L. Lambert, W. Dong, D. W. Winsett, M. K. Selgrade, and M. I. Gilmour, “Residual oil fly ash exposure enhances allergic sensitization to house dust mite,” Toxicology and Applied Pharmacology, vol. 158, no. 3, pp. 269–277, 1999. View at Publisher · View at Google Scholar · View at Scopus
  42. A. L. Lambert, W. Dong, M. K. Selgrade, and M. I. Gilmour, “Enhanced allergic sensitization by residual oil fly ash particles is mediated by soluble metal constituents,” Toxicology and Applied Pharmacology, vol. 165, no. 1, pp. 84–93, 2000. View at Publisher · View at Google Scholar · View at Scopus
  43. M. Løvik, A.-K. Høgseth, P. I. Gaarder, R. Hagemann, and I. Eide, “Diesel exhaust particles and carbon black have adjuvant activity on the local lymph node response and systemic IgE production to ovalbumin,” Toxicology, vol. 121, no. 2, pp. 165–178, 1997. View at Publisher · View at Google Scholar · View at Scopus
  44. M. Van Zijverden, A. Van der Pijl, M. Bol et al., “Diesel exhaust, carbon black, and silica particles display distinct Th1/Th2 modulating activity,” Toxicology and Applied Pharmacology, vol. 168, no. 2, pp. 131–139, 2000. View at Publisher · View at Google Scholar · View at Scopus
  45. J. A. Last, R. Ward, L. Temple, K. E. Pinkerton, and N. J. Kenyon, “Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles,” Inhalation Toxicology, vol. 16, no. 2, pp. 93–102, 2004. View at Publisher · View at Google Scholar · View at Scopus
  46. N. H. Al-Humadi, P. D. Siegel, D. M. Lewis et al., “The effect of diesel exhaust particles (DEP) and carbon black (CB) on thiol changes in pulmonary ovalbumin allergic sensitized brown norway rats,” Experimental Lung Research, vol. 28, no. 5, pp. 333–349, 2002. View at Publisher · View at Google Scholar · View at Scopus
  47. K.-I. Inoue, H. Takano, R. Yanagisawa et al., “Effects of nano particles on antigen-related airway inflammation in mice,” Respiratory Research, vol. 6, article 106, 2005. View at Publisher · View at Google Scholar · View at Scopus
  48. C. De Haar, I. Hassing, M. Bol, R. Bleumink, and R. Pieters, “Ultrafine but not fine particulate matter causes airway inflammation and allergic airway sensitization to co-administered antigen in mice,” Clinical and Experimental Allergy, vol. 36, no. 11, pp. 1469–1479, 2006. View at Publisher · View at Google Scholar · View at Scopus
  49. K. Inoue, H. Takano, R. Yanagisawa et al., “Effects of nanoparticles on lung physiology in the presence or absence of antigen,” International Journal of Immunopathology and Pharmacology, vol. 20, no. 4, pp. 737–744, 2007. View at Google Scholar · View at Scopus
  50. K.-I. Inoue, E. Koike, R. Yanagisawa, S. Hirano, M. Nishikawa, and H. Takano, “Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model,” Toxicology and Applied Pharmacology, vol. 237, no. 3, pp. 306–316, 2009. View at Publisher · View at Google Scholar · View at Scopus
  51. K. Inoue, R. Yanagisawa, E. Koike, M. Nishikawa, and H. Takano, “Repeated pulmonary exposure to single-walled carbon nanotubes exacerbates allergic inflammation of the airway: possible role of oxidative stress,” Free Radical Biology and Medicine, vol. 48, no. 7, pp. 924–934, 2010. View at Publisher · View at Google Scholar · View at Scopus
  52. U. C. Nygaard, J. S. Hansen, M. Samuelsen, T. Alberg, C. D. Marioara, and M. Løvik, “Single-walled and multi-walled carbon nanotubes promote allergic immune responses in mice,” Toxicological Sciences, vol. 109, no. 1, pp. 113–123, 2009. View at Publisher · View at Google Scholar · View at Scopus
  53. J. P. Ryman-Rasmussen, E. W. Tewksbury, O. R. Moss, M. F. Cesta, B. A. Wong, and J. C. Bonner, “Inhaled multiwalled carbon nanotubes potentiate airway fibrosis in murine allergic asthma,” American Journal of Respiratory Cell and Molecular Biology, vol. 40, no. 3, pp. 349–358, 2009. View at Publisher · View at Google Scholar · View at Scopus
  54. S. Hussain, J. A. Vanoirbeek, K. Luyts et al., “Lung exposure to nanoparticles modulates an asthmatic response in a mouse model of asthma,” European Respiratory Journal. In press.
  55. E. Koike, H. Takano, K.-I. Inoue, R. Yanagisawa, and T. Kobayashi, “Carbon black nanoparticles promote the maturation and function of mouse bone marrow-derived dendritic cells,” Chemosphere, vol. 73, no. 3, pp. 371–376, 2008. View at Publisher · View at Google Scholar · View at Scopus
  56. E. Koike, H. Takano, K.-I. Inoue et al., “Pulmonary exposure to carbon black nanoparticles increases the number of antigen-presenting cells in murine lung,” International Journal of Immunopathology and Pharmacology, vol. 21, no. 1, pp. 35–42, 2008. View at Google Scholar · View at Scopus
  57. C. de Haar, M. Kool, I. Hassing, M. Bol, B. N. Lambrecht, and R. Pieters, “Lung dendritic cells are stimulated by ultrafine particles and play a key role in particle adjuvant activity,” Journal of Allergy and Clinical Immunology, vol. 121, no. 5, pp. 1246–1254, 2008. View at Publisher · View at Google Scholar · View at Scopus
  58. W. MacNee and K. Donaldson, “How can ultrafine particles be responsible for increased mortality?” Monaldi Archives for Chest Disease, vol. 55, no. 2, pp. 135–139, 2000. View at Google Scholar · View at Scopus
  59. A. Nemmar, H. Vanbilloen, M. F. Hoylaerts, P. H. M. Hoet, A. Verbruggen, and B. Nemery, “Passage of intratracheally instilled ultrafine particles from the lung into the systemic circulation in hamster,” American Journal of Respiratory and Critical Care Medicine, vol. 164, no. 9, pp. 1665–1668, 2001. View at Google Scholar · View at Scopus