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Journal of Nanomaterials
Volume 2011 (2011), Article ID 423686, 8 pages
http://dx.doi.org/10.1155/2011/423686
Research Article

Surface Modification of Titanium with Heparin-Chitosan Multilayers via Layer-by-Layer Self-Assembly Technique

1Department of Stomatology, Affiliated Hospital Academy of Military, Medical Sciences of Chinese PLA, Beijing 100071, China
2West China College of Stomatology, Sichuan University, Chengdu 610041, China
3Stomatology Department, Xuzhou Medical College, Xuzhou 221000, China
4College of Stomatology, Anhui Medical University, Hefei 230032, China

Received 4 June 2010; Revised 8 August 2010; Accepted 24 September 2010

Academic Editor: Xiaojun Yu

Copyright © 2011 Yao Shu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Albrektsson and M. Jacobsson, “Bone-metal interface in osseointegration,” Journal of Prosthetic Dentistry, vol. 57, no. 5, pp. 597–607, 1987. View at Google Scholar · View at Scopus
  2. D. A. Puleo and A. Nanci, “Understanding and controlling the bone-implant interface,” Biomaterials, vol. 20, no. 23-24, pp. 2311–2321, 1999. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Tirrell, E. Kokkoli, and M. Biesalski, “The role of surface science in bioengineered materials,” Surface Science, vol. 500, no. 1–3, pp. 61–83, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. C. M. Stanford, “Surface modifications of implants,” Oral and Maxillofacial Surgery Clinics of North America, vol. 14, no. 1, pp. 39–51, 2002. View at Publisher · View at Google Scholar · View at Scopus
  5. Q. Liu, J. Ding, F. K. Mante, S. L. Wunder, and G. R. Baran, “The role of surface functional groups in calcium phosphate nucleation on titanium foil: a self-assembled monolayer technique,” Biomaterials, vol. 23, no. 15, pp. 3103–3111, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Nanci, J. D. Wuest, L. Peru et al., “Chemical modification of titanium surfaces for covalent attachment of biological molecules,” Journal of Biomedical Materials Research, vol. 40, no. 2, pp. 324–335, 1998. View at Google Scholar · View at Scopus
  7. T. Salditt and U. S. Schubert, “Layer-by-layer self-assembly of supramolecular and biomolecular films,” Reviews in Molecular Biotechnology, vol. 90, no. 1, pp. 55–70, 2002. View at Publisher · View at Google Scholar · View at Scopus
  8. K. Cai, A. Rechtenbach, J. Hao, J. Bossert, and K. D. Jandt, “Polysaccharide-protein surface modification of titanium via a layer-by-layer technique: characterization and cell behaviour aspects,” Biomaterials, vol. 26, no. 30, pp. 5960–5971, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. G. G. S. Grant, D. S. Koktysh, B. Yun, R. L. Matts, and N. A. Kotov, “Layer-by-layer assembly of collagen thin films: controlled thickness and biocompatibility,” Biomedical Microdevices, vol. 3, no. 4, pp. 301–306, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. G. Decher, “Fuzzy nanoassemblies: toward layered polymeric multicomposites,” Science, vol. 277, no. 5330, pp. 1232–1237, 1997. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Tryoen-Tth, D. Vautier, Y. Haikel et al., “Viability, adhesion, and bone phenotype of osteoblast-like cells on polyelectrolyte multilayer films,” Journal of Biomedical Materials Research, vol. 60, no. 4, pp. 657–667, 2002. View at Publisher · View at Google Scholar · View at Scopus
  12. L. Richert, P. Lavalle, E. Payan et al., “Layer by layer buildup of polysaccharide films: physical chemistry and cellular adhesion aspects,” Langmuir, vol. 20, no. 2, pp. 448–458, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Cai, Y. Hu, K. D. Jandt, and Y. Wang, “Surface modification of titanium thin film with chitosan via electrostatic self-assembly technique and its influence on osteoblast growth behavior,” Journal of Materials Science: Materials in Medicine, vol. 19, no. 2, pp. 499–506, 2008. View at Publisher · View at Google Scholar · View at Scopus
  14. K. Cai, Y. Hu, and K. D. Jandt, “Surface engineering of titanium thin films with silk fibroin via layer-by-layer technique and its effects on osteoblast growth behavior,” Journal of Biomedical Materials Research A, vol. 82, no. 4, pp. 927–935, 2007. View at Publisher · View at Google Scholar · View at Scopus
  15. Y. Hu, K. Cai, Z. Luo et al., “Surface mediated in situ differentiation of mesenchymal stem cells on gene-functionalized titanium films fabricated by layer-by-layer technique,” Biomaterials, vol. 30, no. 21, pp. 3626–3635, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. J. K. Suh and H. W. Matthew, “Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review,” Biomaterials, vol. 21, no. 24, pp. 2589–2598, 2000. View at Google Scholar · View at Scopus
  17. T. Albrektsson and H. A. Hansson, “An ultrastructural characterization of the interface between bone and sputtered titanium or stainless steel surfaces,” Biomaterials, vol. 7, no. 3, pp. 201–205, 1986. View at Google Scholar · View at Scopus
  18. S. Mohan and D. J. Baylink, “Bone growth factors,” Clinical Orthopaedics and Related Research, no. 263, pp. 30–48, 1991. View at Google Scholar · View at Scopus
  19. L. S. Beck, E. P. Amento, Y. Xu et al., “TGF-β1 induces bone closure of skull defects: temporal dynamics of bone formation in defects exposed to rhTGF-β1,” Journal of Bone and Mineral Research, vol. 8, no. 6, pp. 753–761, 1993. View at Google Scholar · View at Scopus
  20. B. Zhao, T. Katagiri, H. Toyoda et al., “Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2,” Journal of Biological Chemistry, vol. 281, no. 32, pp. 23246–23253, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. F. Blanquaert, J. L. Saffar, M. L. Colombier, G. Carpentier, D. Barritault, and J. P. Caruelle, “Heparan-like molecules induce the repair of skull defects,” Bone, vol. 17, no. 6, pp. 499–506, 1995. View at Publisher · View at Google Scholar · View at Scopus
  22. E. Khor and L. Y. Lim, “Implantable applications of chitin and chitosan,” Biomaterials, vol. 24, no. 13, pp. 2339–2349, 2003. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Berger, M. Reist, J. M. Mayer, O. Felt, and R. Gurny, “Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications,” European Journal of Pharmaceutics and Biopharmaceutics, vol. 57, no. 1, pp. 35–52, 2004. View at Publisher · View at Google Scholar · View at Scopus
  24. D. T. Wassell and G. Embery, “Adsorption of bovine serum albumin on to titanium powder,” Biomaterials, vol. 17, no. 9, pp. 859–864, 1996. View at Publisher · View at Google Scholar · View at Scopus
  25. B. Feng, J. Weng, B. C. Yang et al., “Surface characterization of titanium and adsorption of bovine serum albumin,” Materials Characterization, vol. 49, no. 2, pp. 129–137, 2002. View at Publisher · View at Google Scholar · View at Scopus
  26. E. Jansson and P. Tengvall, “Adsorption of albumin and IgG to porous and smooth titanium,” Colloids and Surfaces B: Biointerfaces, vol. 35, no. 1, pp. 45–51, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. H. M. Kim, F. Miyaji, T. Kokubo, and T. Nakamura, “Effect of heat treatment on apatite-forming ability of Ti metal induced by alkali treatment,” Journal of Materials Science: Materials in Medicine, vol. 8, no. 6, pp. 341–347, 1997. View at Publisher · View at Google Scholar · View at Scopus
  28. K. Cai, K. Yao, S. Lin et al., “Poly(D,L-lactic acid) surfaces modified by silk fibroin: effects on the culture of osteoblast in vitro,” Biomaterials, vol. 23, no. 4, pp. 1153–1160, 2002. View at Publisher · View at Google Scholar · View at Scopus
  29. M. C. Serrano, R. Pagani, M. Vallet-Regí et al., “In vitro biocompatibility assessment of poly(ε-caprolactone) films using L929 mouse fibroblasts,” Biomaterials, vol. 25, no. 25, pp. 5603–5611, 2004. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Sibilla, A. Sereni, G. Aguiari et al., “Effects of a hydroxyapatite-based biomaterial on gene expression in osteoblast-like cells,” Journal of Dental Research, vol. 85, no. 4, pp. 354–358, 2006. View at Publisher · View at Google Scholar · View at Scopus
  31. L. Lu, L. Kam, M. Hasenbein et al., “Retinal pigment epithelial cell function on substrates with chemically micropatterned surfaces,” Biomaterials, vol. 20, no. 23-24, pp. 2351–2361, 1999. View at Publisher · View at Google Scholar · View at Scopus
  32. Y. Takagishi, T. Kawakami, Y. Hara, M. Shinkai, T. Takezawa, and T. Nagamune, “Bone-like tissue formation by three-dimensional culture of MG63 osteosarcoma cells in gelatin hydrogels using calcium-enriched medium,” Tissue Engineering, vol. 12, no. 4, pp. 927–937, 2006. View at Publisher · View at Google Scholar · View at Scopus
  33. J. D. Bumgardner, R. Wiser, P. D. Gerard et al., “Chitosan: potential use as a bioactive coating for orthopaedic and craniofacial/dental implants,” Journal of Biomaterials Science, Polymer Edition, vol. 14, no. 5, pp. 423–438, 2003. View at Publisher · View at Google Scholar · View at Scopus