5-Fluorouracil Encapsulated Chitosan Nanoparticles for pH-Stimulated Drug Delivery: Evaluation of Controlled Release Kinetics

Table 3

Average particle size of chitosan nanoparticles prepared at different amounts of Tween 80.¹

Tween 80 (%)	1.25 mg/mL chitosan : 1.25 mg/mL TPP (2.5 : 1)  (v/v)	0.75 mg/mL chitosan : 0.5 mg/mL TPP (2 : 1)  (v/v)
0	>1000*	>1000*
0.5	393.1±1.8 (PDI: 0.443)	148.8±1.1 (PDI: 0.066)
1.0	432.8±10.0 (PDI: 0.436)	177.0±3.2 (PDI: 0.090)

¹Measurements are performed three times.
*PDI > 1.00