Effect of Surface-Modified Paclitaxel Nanowires on U937 Cells In Vitro: A Novel Drug Delivery Vehicle
(a) Drug-loaded nanoparticle with cluster of drug molecules randomly distributed though out the vehicle matrix. Most of the drug is distributed on the surface of the matrix, which leads to the burst effect. (b) SM-PN with an exact diameter and length. The entire drug is located inside the vehicle (ODS shell). The alkyl group R is anchored inside the drug nanowire with the Si–OH sticking out. ODS stands for octadecylsiloxane.
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