Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2012, Article ID 375496, 7 pages
http://dx.doi.org/10.1155/2012/375496
Research Article

Effect of Size, Shape, and Surface Modification on Cytotoxicity of Gold Nanoparticles to Human HEp-2 and Canine MDCK Cells

1Department of Physics, University of Strathclyde, John Anderson Building, 107 Rotternrow, Glasgow G4 0NG, UK
2Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK
3Institute of Immunopathology, School of Life Science & Technology, Xi'an Jiaotong University, Shanxi 710061, China

Received 25 March 2012; Revised 20 April 2012; Accepted 23 April 2012

Academic Editor: Grégory Guisbiers

Copyright © 2012 Yinan Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [58 citations]

The following is the list of published articles that have cited the current article.

  • Y. Chen, Y. Zhang, D. J. S. Birch, and A. S. Barnard, “Creation and luminescence of size-selected gold nanorods,” Nanoscale, vol. 4, no. 16, pp. 5017–5022, 2012. View at Publisher · View at Google Scholar
  • Darcy E. Wagner, Kathryn M. Eisenmann, Andrea L. Nestor-Kalinoski, and Sarit B. Bhaduri, “A microwave-assisted solution combustion synthesis to produce europium-doped calcium phosphate nanowhiskers for bioimaging applications,” Acta Biomaterialia, 2013. View at Publisher · View at Google Scholar
  • Marcin Runowski, Krystyna Dabrowska, Tomasz Grzyb, Paulina Miernikiewicz, and Stefan Lis, “Core/shell-type nanorods of Tb3+-doped LaPO4, modified with amine groups, revealing reduced cytotoxicity,” Journal of Nanoparticle Research, vol. 15, no. 11, 2013. View at Publisher · View at Google Scholar
  • Sanjeev Kumar Mahto, Verena Charwat, Peter Ertl, Barbara Rothen-Rutishauser, Seog Woo Rhee, and Josué Sznitman, “Microfluidic platforms for advanced risk assessments of nanomaterials,” Nanotoxicology, pp. 1–15, 2014. View at Publisher · View at Google Scholar
  • Maria Filippousi, Maria Katsikini, Eleni Paloura, Gustaaf Van Tendeloo, Ilias Efthimiopoulos, Mavroeidis Angelakeris, Yuejian Wang, and Demetris Zamboulis, “Surfactant effects on the structural and magnetic properties of iron oxide nanoparticles,” Journal of Physical Chemistry C, vol. 118, no. 29, pp. 16209–16217, 2014. View at Publisher · View at Google Scholar
  • Nicole M. Schaeublin, Kristen K. Comfort, John J. Schlager, Shashi Bala Singh, and Saber M. Hussainpp. 69–80, 2014. View at Publisher · View at Google Scholar
  • Daniel N. Grant, Matthew J. Cozad, David A. Grant, Richard A. White, and Sheila A. Grant, “ In vitro electromagnetic stimulation to enhance cell proliferation in extracellular matrix constructs with and without metallic nanoparticles ,” Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014. View at Publisher · View at Google Scholar
  • Megha N. Murthy, Raviraj V. Suresh, Dinesh S. Manjegowda, Nallur B. Ramachandra, Avinash M. Veerappa, Kusuma Lingaiah, and Sangeetha Vishweswaraiah, “Impact of copy number variations burden on coding genome in humans using integrated high resolution arrays,” Genetics Research, vol. 96, 2014. View at Publisher · View at Google Scholar
  • Ying Liu, and I-Ming Hsing, “Cancer Specific Targeting by Glucosamine Coated Gold Nanoparticles In Vitro and In Vivo,” Journal Of Biomaterials And Tissue Engineering, vol. 5, no. 9, pp. 687–696, 2015. View at Publisher · View at Google Scholar
  • Yinan Zhang, Guoke Wei, Jun Yu, David J. S. Birch, and Yu Chen, “Surface plasmon enhanced energy transfer between gold nanorods and fluorophores: Application to endocytosis study and RNA detection,” Faraday Discussions, vol. 178, pp. 383–394, 2015. View at Publisher · View at Google Scholar
  • Stefaan J. Soenen, Wolfgang J. Parak, Joanna Rejman, and Bella Manshian, “(Intra)Cellular Stability of Inorganic Nanoparticles: Effects on Cytotoxicity, Particle Functionality, and Biomedical Applications,” Chemical Reviews, vol. 115, no. 5, pp. 2109–2135, 2015. View at Publisher · View at Google Scholar
  • Bo-Ji Liu, Dan-Dan Li, Hui-Xiong Xu, Le-Hang Guo, Yi-Feng Zhang, Jun-Mei Xu, Chang Liu, Lin-Na Liu, Xiao-Long Li, Xiao-Hong Xu, Shen Qu, and Mingzhao Xing, “Quantitative Shear Wave Velocity Measurement On Acoustic Radiation Force Impulse Elastography For Differential Diagnosis Between Benign And Malignant ,” Ultrasound In Medicine And Biology, vol. 41, no. 12, pp. 3035–3043, 2015. View at Publisher · View at Google Scholar
  • Benny Chung-ying Zee, Xiang Qian Lao, WenJun Ma, Roger Yat-Nork Chung, YongHui Zhang, YanJun Xu, XiaoJun Xu, ShaoPing Nie, QiuMao Cai, Liang Xia, XueFen Su, Lei Jin, and Tony Tam, “The diminishing socioeconomic disparity in obesity in a Chinese population with rapid economic development: analysis of serial cross-sectional health ,” Bmc Public Health, vol. 15, 2015. View at Publisher · View at Google Scholar
  • Gulshan Kumar, and Anil Kumar Singh, “Reference gene validation for qRT-PCR based gene expression studies in different developmental stages and under biotic stress in apple,” Scientia Horticulturae, vol. 197, pp. 597–606, 2015. View at Publisher · View at Google Scholar
  • Geert Geeven, Yun Zhu, Byung Ju Kim, Boris A. Bartholdy, Seung-Min Yang, Todd S. Macfarlan, Wesley D. Gifford, Samuel L. Pfaff, Marjon J. A. M. Verstegen, Hugo Pinto, Marit W. Vermunt, Menno P. Creyghton, Patrick J. Wijchers, John A. Stamatoyannopoulos, Arthur I. Skoultchi, and Wouter de Laat, “Local compartment changes and regulatory landscape alterations in histone H1-depleted cells,” Genome Biology, vol. 16, 2015. View at Publisher · View at Google Scholar
  • Ghobad Azizi, James M. Keller, Michelle L. Mayo, Kele Piper, David Puett, Karly M. Earp, and Carl D. Malchoff, “Thyroid Nodules And Shear Wave Elastography: A New Tool In Thyroid Cancer Detection,” Ultrasound In Medicine And Biology, vol. 41, no. 11, pp. 2855–2865, 2015. View at Publisher · View at Google Scholar
  • Hannah J. Stewart, and Sygal Amitay, “Modality-specificity of Selective Attention Networks,” Frontiers In Psychology, vol. 6, 2015. View at Publisher · View at Google Scholar
  • Yusuf Valentino Kaneti, Chuyang Chen, Minsu Liu, Xiaochun Wang, Jia Lin Yang, Robert Allen Taylor, Xuchuan Jiang, and Aibing Yu, “Carbon-Coated Gold Nanorods: A Facile Route to Biocompatible Materials for Photothermal Applications,” ACS Applied Materials & Interfaces, 2015. View at Publisher · View at Google Scholar
  • Yi-Feng Zhang, Hui-Xiong Xu, Jun-Mei Xu, Chang Liu, Le-Hang Guo, Lin-Na Liu, Jing Zhang, Xiao-Hong Xu, Shen Qu, and Mingzhao Xing, “Acoustic Radiation Force Impulse Elastography In The Diagnosis Of Thyroid Nodules: Useful Or Not Useful?,” Ultrasound In Medicine And Biology, vol. 41, no. 10, pp. 2581–2593, 2015. View at Publisher · View at Google Scholar
  • BaoXian Liu, YanLing Zheng, QuanYuan Shan, Ying Lu, ManXia Lin, WenShuo Tian, and XiaoYan Xie, “Elastography by acoustic radiation force impulse technology for differentiation of benign and malignant breast lesions: a meta-analysis,” Journal of Medical Ultrasonics, 2015. View at Publisher · View at Google Scholar
  • Christiane M. Nday, Eleftherios Halevas, Graham E. Jackson, and Athanasios Salifoglou, “Quercetin Encapsulation in Modified Silica Nanoparticles. Potential Use Against Cu(II)-Induced Oxidative Stress in Neurodegeneration,” Journal of Inorganic Biochemistry, 2015. View at Publisher · View at Google Scholar
  • Dipranjan Laha, Arindam Pramanik, Sourav Chattopadhyay, Sandip kumar Dash, Somenath Roy, Panchanan Pramanik, and Parimal Karmakar, “Folic acid modified copper oxide nanoparticles for targeted delivery in in vitro and in vivo systems,” RSC Adv., vol. 5, no. 83, pp. 68169–68178, 2015. View at Publisher · View at Google Scholar
  • Thangavelu Raja muthuramalingam, Chandirasekar Shanmugam, Dharanivasan Gunasekaran, Nallusamy Duraisamy, Rajendran Nagappan, and Kathiravan Krishnan, “Bioactive bile salt-capped silver nanoparticles activity against destructive plant pathogenic fungi through in vitro system,” RSC Adv., vol. 5, no. 87, pp. 71174–71182, 2015. View at Publisher · View at Google Scholar
  • Y. U. Ping, and Y. U. Ping, “Multi-model modeling and its application of urban sewage treatment based on clustering analysis,” 2015 Global Conference On Polymer And Composite Materials (Pcm2015), vol. 87, 2015. View at Publisher · View at Google Scholar
  • Consolacion Melguizo, Laura Cabeza, Jose Prados, Raul Ortiz, Octavio Caba, Ana R. Rama, Angel V. Delgado, and Jose L. Arias, “Enhanced antitumoral activity of doxorubicin against lung cancer cells using biodegradable poly(butylcyanoacrylate) nanoparticles,” Drug Design Development And Therapy, vol. 9, pp. 6433–6444, 2015. View at Publisher · View at Google Scholar
  • Guoke Wei, Jun Yu, Jinliang Wang, Peng Gu, David J. S. Birch, and Yu Chen, “Hairpin DNA-functionalized gold nanorods for mRNA detection in homogenous solution,” Journal of Biomedical Optics, vol. 21, no. 9, 2016. View at Publisher · View at Google Scholar
  • Baoshan Xing, Chad D. Vecitis, Nicola Senesi, Sukru Gokhan Elci, Alyssa L. M. Marsico, Yuqing Xing, Bo Yan, and Richard W. Vachet, “Mass Spectrometric Methods for Investigating the Influence of Surface Chemistry on the Fate of Core-Shell Nanoparticles in Biological and Environmental Samples,” Engineered Nanoparticles and the Environment: Biophysicochemical Processes and Toxicity, pp. 31–52, 2016. View at Publisher · View at Google Scholar
  • Amel Hanini, Mohamed El Massoudi, Julie Gavard, Kamel Kacem, Souad Ammar, and Ouajdi Souilem, “Nanotoxicological study of polyol-made cobalt-zinc ferrite nanoparticles in rabbit,” Environmental Toxicology and Pharmacology, vol. 45, pp. 321–327, 2016. View at Publisher · View at Google Scholar
  • Valeria S. Marangoni, Juliana Cancino-Bernardi, and Valtencir Zucolotto, “Synthesis, Physico-Chemical Properties, and Biomedical Applications of Gold Nanorods-A Review,” Journal Of Biomedical Nanotechnology, vol. 12, no. 6, pp. 1136–1158, 2016. View at Publisher · View at Google Scholar
  • Valeria S. Marangoni, Juliana Cancino-Bernardi, and Valtencir Zucolotto, “Synthesis, physico-chemical properties, and biomedical applications of gold nanorods-A review,” Journal of Biomedical Nanotechnology, vol. 12, no. 6, pp. 1136–1158, 2016. View at Publisher · View at Google Scholar
  • Juliana Martins de Souza e Silva, Talita Diniz Melo Hanchuk, Murilo Izidoro Santos, Jörg Kobarg, Marcio Chaim Bajgelman, and Mateus Borba Cardoso, “Viral Inhibition Mechanism Mediated by Surface-Modified Silica Nanoparticles,” ACS Applied Materials & Interfaces, 2016. View at Publisher · View at Google Scholar
  • Pedro Vieira, Patrícia Rijo, Lia Ascensão, João M. Pinto Coelho, Ana Gabriel, Catarina Oliveira Silva, Catarina Pinto Reis, Jesús Molpeceres, Amílcar Roberto, Ana Sofia Fernandes, and Ricardo Gomes, “Bioproduction of gold nanoparticles for photothermal therapy,” Therapeutic Delivery, vol. 7, no. 5, pp. 287–304, 2016. View at Publisher · View at Google Scholar
  • Seonmi Baek, Rajendra K. Singh, Tae-Hyun Kim, Jae-won Seo, Ueon Sang Shin, Wojciech Chrzanowski, and Hae-Won Kim, “Triple Hit with Drug Carriers: pH- and Temperature-Responsive Theranostics for Multimodal Chemo- and Photothermal Therapy and Diagnostic Applications,” ACS Applied Materials & Interfaces, 2016. View at Publisher · View at Google Scholar
  • Sandra P. Sanchez-Rodriguez, Jeremy P. Sauer, Sarah A. Stanley, Xi Qian, Andrew Gottesdiener, Jeffrey M. Friedman, and Jonathan S. Dordick, “Plasmonic activation of gold nanorods for remote stimulation of calcium signaling and protein expression in HEK 293T cells,” Biotechnology and Bioengineering, vol. 113, no. 10, pp. 2228–2240, 2016. View at Publisher · View at Google Scholar
  • Zhen-lu Li, Hong-ming Ding, and Yu-qiang Ma, “Interaction of peptides with cell membranes: insights from molecular modeling,” Journal Of Physics-Condensed Matter, vol. 28, no. 8, 2016. View at Publisher · View at Google Scholar
  • Rajeshwari, Amitava Mukherjee, Barsha Roy, and Natarajan Chandrasekaran, “Cytogenetic evaluation of gold nanorods using Allium cepa test,” Plant Physiology and Biochemistry, vol. 109, pp. 209–219, 2016. View at Publisher · View at Google Scholar
  • Elissa M. Grzincic, Catherine J. Murphy, and Priscila Falagan-Lotsch, “One low-dose exposure of gold nanoparticles induces long-term changes in human cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 47, pp. 13318–13323, 2016. View at Publisher · View at Google Scholar
  • Jieun Koh, Hee Jung Moon, Jeong Seon Park, Soo Jin Kim, Ha Yan Kim, Eun-Kyung Kim, and Jin Young Kwak, “Variability In Interpretation Of Ultrasound Elastography And Gray-Scale Ultrasound In Assessing Thyroid Nodules,” Ultrasound In Medicine And Biology, vol. 42, no. 1, pp. 51–59, 2016. View at Publisher · View at Google Scholar
  • Xiaohan Zou, Yuwei He, Jinping Qiao, Chunlei Zhang, and Zhengyu Cao, “The natural scorpion peptide, BmK NT1 activates voltage-gated sodium channels and produces neurotoxicity in primary cultured cerebellar granule cells,” Toxicon, vol. 109, pp. 33–41, 2016. View at Publisher · View at Google Scholar
  • Ryan J. Haasl, and Bret A. Payseur, “Fifteen years of genomewide scans for selection: trends, lessons and unaddressed genetic sources of complication,” Molecular Ecology, vol. 25, no. 1, pp. 5–23, 2016. View at Publisher · View at Google Scholar
  • Kinga Matula, Lukasz Richter, Witold Adamkiewicz, Bo Akerstrom, Jan Paczesny, and Robert Holyst, “Influence of nanomechanical stress induced by ZnO nanoparticles of different shapes on the viability of cells,” Soft Matter, vol. 12, no. 18, pp. 4162–4169, 2016. View at Publisher · View at Google Scholar
  • Saud Alarifi, Daoud Ali, and Saad Alkahtani, “Mechanistic investigation of toxicity of chromium oxide nanoparticles in murine fibrosarcoma cells,” International Journal Of Nanomedicine, vol. 11, pp. 1253–1259, 2016. View at Publisher · View at Google Scholar
  • Kaniknun Sreejivungsa, Nattawut Suchaichit, Panawan Moosophon, and Apiwat Chompoosor, “Light-Regulated Release of Entrapped Drugs from Photoresponsive Gold Nanoparticles,” Journal of Nanomaterials, vol. 2016, pp. 1–7, 2016. View at Publisher · View at Google Scholar
  • M. Almada, B.H. Leal-Martínez, N. Hassan, M.J. Kogan, M.G. Burboa, A. Topete, M.A. Valdez, and J. Juárez, “Photothermal conversion efficiency and cytotoxic effect of gold nanorods stabilized with chitosan, alginate and poly(vinyl alcohol),” Materials Science and Engineering: C, vol. 77, pp. 583–593, 2017. View at Publisher · View at Google Scholar
  • Pavla Sauerová, Tereza Pilgrová, Miloslav Pekař, and Marie Hubálek Kalbáčová, “Hyaluronic acid in complexes with surfactants: the efficient tool for reduction of the cytotoxic effect of surfactants on human cell types,” International Journal of Biological Macromolecules, 2017. View at Publisher · View at Google Scholar
  • Anna Woźniak, Anna Malankowska, Grzegorz Nowaczyk, Bartosz F. Grześkowiak, Karol Tuśnio, Ryszard Słomski, Adriana Zaleska-Medynska, and Stefan Jurga, “Size and shape-dependent cytotoxicity profile of gold nanoparticles for biomedical applications,” Journal of Materials Science: Materials in Medicine, vol. 28, no. 6, 2017. View at Publisher · View at Google Scholar
  • Kaulen, Simon, Offenhäusser, Mayer, and Tran, “Surface coupling strength of gold nanoparticles affects cytotoxicity towards neurons,” Biomaterials Science, vol. 5, no. 5, pp. 1051–1060, 2017. View at Publisher · View at Google Scholar
  • Yinan Zhang, Yu Chen, Jun Yu, and David J. S. Birch, “Endosytosis study of gold nanoparticles through FRET-FLIM approach,” Proceedings of the 13th IASTED International Conference on Biomedical Engineering, BioMed 2017, pp. 26–31, 2017. View at Publisher · View at Google Scholar
  • Kiran Kuruvinashetti, Ahmad Sohrabi Kashani, Simona Badilescu, Daniel Beaudet, Alisa Piekny, and Muthukumaran Packirisamy, “Intracellular Localized Surface Plasmonic Sensing for Subcellular Diagnosis,” Plasmonics, 2017. View at Publisher · View at Google Scholar
  • Yuran Tang, Qin Liu, Xue Yang, Min Wei, and Mingxiao Zhang, “Copper oxide coated gold Nanorods like a film: A facile route to nanocomposites for electrochemical application,” Journal of Electroanalytical Chemistry, 2017. View at Publisher · View at Google Scholar
  • Anil B. Jindal, “The effect of particle shape on cellular interaction and drug delivery applications of micro- and nanoparticles,” International Journal of Pharmaceutics, vol. 532, no. 1, pp. 450–465, 2017. View at Publisher · View at Google Scholar
  • Swathi Sudhakar, Ethayaraja Mani, Poornima Budime Santhosh, Neethu Thomas, and Anju Chadha, “Phospholipid stabilized gold nanorods: Towards improved colloidal stability and biocompatibility,” Physical Chemistry Chemical Physics, vol. 19, no. 28, pp. 18494–18504, 2017. View at Publisher · View at Google Scholar
  • Irshad Ahmad Wani, and Tokeer Ahmad, “Understanding Toxicity of Nanomaterials in Biological Systems,” Applying Nanotechnology for Environmental Sustainability, pp. 403–427, 2017. View at Publisher · View at Google Scholar
  • Jigna Shah, and Parmi Patel, “Safety and toxicological considerations of nanomedicines: The future directions,” Current Clinical Pharmacology, vol. 12, no. 2, pp. 73–82, 2017. View at Publisher · View at Google Scholar
  • Irshad Ahmad Wani, and Tokeer Ahmad, “Understanding Toxicity of Nanomaterials in Biological Systems,” Materials Science and Engineering: Concepts, Methodologies, Tools, and Applications, pp. 1533–1557, 2017. View at Publisher · View at Google Scholar
  • Irshad Ahmad Wani, and Tokeer Ahmad, “Understanding Toxicity of Nanomaterials in Biological Systems,” Pharmaceutical Sciences: Breakthroughs in Research and Practice, pp. 1492–1516, 2017. View at Publisher · View at Google Scholar
  • Ben Allan Russell, Barbara Jachimska, and Yu Chen, “Polyallylamine hydrochloride coating enhances the fluorescence emission of Human Serum Albumin encapsulated gold nanoclusters,” Journal of Photochemistry and Photobiology B: Biology, vol. 187, pp. 131–135, 2018. View at Publisher · View at Google Scholar
  • Praveen Kumar, Uday Burman, and Ramesh K. Kaul, “Ecological Risks of Nanoparticles,” Nanomaterials in Plants, Algae, and Microorganisms, pp. 429–452, 2018. View at Publisher · View at Google Scholar