Research Article

Effect of Size, Shape, and Surface Modification on Cytotoxicity of Gold Nanoparticles to Human HEp-2 and Canine MDCK Cells

Figure 5

Confocal microscopy on HEp-2 cells for activated caspases (in red) and nuclei (in blue). All images were taken 5 h after GNR treatment. (A) negative control (untreated cells); (B), (C), and (D), respectively, were cells treated with GNR-1 at the concentration of 1-, 5- and 10-fold of 10−12 M of stock solution. Similarly, (E), (F), and (G) were cells treated with GNR-2, and (H), (I), (J) were cells treated with GNR-3, respectively, at the concentrations of 1-, 5-, and 10-fold of the 10−12 M solutions.
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