Research Article

Elimination of Tumor Cells Using Folate Receptor Targeting by Antibody-Conjugated, Gold-Coated Magnetite Nanoparticles in a Murine Breast Cancer Model

Figure 5

4T1 cells were labeled for FR using Au-coated magnetite nanoparticles without (−OMF, upper panels) or with (+OMF, lower panels) exposure to the OMF prior to staining with calcein-AM and PI. In the overlay, yellow indicates colocalization of green and red fluorescence. Apparent cell debris or cell remnants are indicated by the arrow in the lower phase image. Images taken at 200x magnification.
431012.fig.005