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Journal of Nanomaterials
Volume 2012 (2012), Article ID 730746, 12 pages
http://dx.doi.org/10.1155/2012/730746
Research Article

Green Synthesis of Robust, Biocompatible Silver Nanoparticles Using Garlic Extract

Gregory Von White II,1 Petra Kerscher,1 Ryan M. Brown,1 Jacob D. Morella,1 William McAllister,2 Delphine Dean,2 and Christopher L. Kitchens1

1Department of Chemical and Biomolecular Engineering, Clemson University, Clemson, SC 29634, USA
2Department of Bioengineering, Clemson University, Clemson, SC 29634, USA

Received 22 January 2012; Accepted 16 February 2012

Academic Editor: Chunyi Zhi

Copyright © 2012 Gregory Von White et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. V. H. Grassian, “When size really matters: size-dependent properties and surface chemistry of metal and metal oxide nanoparticles in gas and liquid phase environments,” Journal of Physical Chemistry C, vol. 112, no. 47, pp. 18303–18313, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. P. K. Jain, K. S. Lee, I. H. El-Sayed, and M. A. El-Sayed, “Calculated absorption and scattering properties of gold nanoparticles of different size, shape, and composition: applications in biological imaging and biomedicine,” Journal of Physical Chemistry B, vol. 110, no. 14, pp. 7238–7248, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Liu and Z. J. Zhang, “Size-dependent superparamagnetic properties of Mn spinel ferrite nanoparticles synthesized from reverse micelles,” Chemistry of Materials, vol. 13, no. 6, pp. 2092–2096, 2001. View at Google Scholar · View at Scopus
  4. X. H. N. Xu, S. Huang, W. Brownlow, K. Salaita, and R. B. Jeffers, “Size and temperature dependence of surface plasmon absorption of gold nanoparticles induced by tris(2,2′-bipyridine)ruthenium(II),” Journal of Physical Chemistry B, vol. 108, no. 40, pp. 15543–15551, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. D. Manno, E. Filippo, M. Di Giulio, and A. Serra, “Synthesis and characterization of starch-stabilized Ag nanostructures for sensors applications,” Journal of Non-Crystalline Solids, vol. 354, no. 52–54, pp. 5515–5520, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. J. Kim, Y. S. Yang, S. -C. Ha et al., “Mixed-ligand nanoparticles of chlorobenzenemethanethiol and n-octanethiol as chemical sensors,” Sensors and Actuators B, vol. 106, no. 1, pp. 189–198, 2005. View at Publisher · View at Google Scholar
  7. A. Prakash, J. Ouyang, J. L. Lin, and Y. Yang, “Polymer memory device based on conjugated polymer and gold nanoparticles,” Journal of Applied Physics, vol. 100, no. 5, Article ID 054309, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. A. D. LaLonde, M. G. Norton, D. Zhang et al., “Controlled growth of gold nanoparticles on silica nanowires,” Journal of Materials Research, vol. 20, no. 11, pp. 3021–3027, 2005. View at Publisher · View at Google Scholar · View at Scopus
  9. M. Brust, M. Walker, D. Bethell, D. J. Schiffrin, and R. Whyman, “Synthesis of thiol-derivatised gold nanoparticles in a two-phase liquid-liquid system,” Journal of the Chemical Society, Chemical Communications, no. 7, pp. 801–802, 1994. View at Publisher · View at Google Scholar · View at Scopus
  10. A. P. Herrera, O. Resto, J. G. Briano, and C. Rinaldi, “Synthesis and agglomeration of gold nanoparticles in reverse micelles,” Nanotechnology, vol. 16, no. 7, pp. S618–S625, 2005. View at Publisher · View at Google Scholar · View at Scopus
  11. C. L. Kitchens, M. C. McLeod, and C. B. Roberts, “Chloride ion effects on synthesis and directed assembly of copper nanoparticles in liquid and compressed alkane microemulsions,” Langmuir, vol. 21, no. 11, pp. 5166–5173, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. M.-L. Wu and L.-B. Lai, “Synthesis of Pt/Ag bimetallic nanoparticles in water-in-oil microemulsions,” Colloids and Surfaces A, vol. 244, no. 1–3, pp. 149–157, 2004. View at Publisher · View at Google Scholar
  13. J. Liu, J. Sutton, and C. B. Roberts, “Synthesis and extraction of monodisperse sodium carboxymethylcellulose-stabilized platinum nanoparticles for the self-assembly of ordered arrays,” Journal of Physical Chemistry C, vol. 111, no. 31, pp. 11566–11576, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. J. Liu, M. Anand, and C. B. Roberts, “Synthesis and extraction of β-D-glucose-stabilized au nanoparticles processed into low-defect, wide-area thin films and ordered arrays using CO2-expanded liquids,” Langmuir, vol. 22, no. 9, pp. 3964–3971, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. J. Liu, F. He, T. M. Gunn, D. Zhao, and C. B. Roberts, “Precise seed-mediated growth and size-controlled synthesis of palladium nanoparticles using a green chemistry approach,” Langmuir, vol. 25, no. 12, pp. 7116–7128, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Y. Moon, T. Kusunose, and T. Sekino, “CTAB-assisted synthesis of size- and shape-controlled gold nanoparticles in SDS aqueous solution,” Materials Letters, vol. 63, no. 23, pp. 2038–2040, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. Z. M. Sui, X. Chen, L. Y. Wang et al., “Capping effect of CTAB on positively charged Ag nanoparticles,” Physica E, vol. 33, no. 2, pp. 308–314, 2006. View at Publisher · View at Google Scholar
  18. S. C. Boca and S. Astilean, “Detoxification of gold nanorods by conjugation with thiolated poly(ethylene glycol) and their assessment as SERS-active carriers of Raman tags,” Nanotechnology, vol. 21, no. 23, Article ID 235601, 2010. View at Publisher · View at Google Scholar
  19. M. C. Urbina, S. Zinoveva, T. Miller, C. M. Sabliov, W. T. Monroe, and C. S. S. R. Kumar, “Investigation of magnetic nanoparticle-polymer composites for multiple-controlled drug delivery,” Journal of Physical Chemistry C, vol. 112, no. 30, pp. 11102–11108, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. R. Bhattacharya, C. R. Patra, A. Earl et al., “Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells,” Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 3, no. 3, pp. 224–238, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. R. E. Rosensweig, “Heating magnetic fluid with alternating magnetic field,” Journal of Magnetism and Magnetic Materials, vol. 252, no. 1–3, pp. 370–374, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. C. Greulich, S. Kittler, M. Epple, G. Muhr, and M. Köller, “Studies on the biocompatibility and the interaction of silver nanoparticles with human mesenchymal stem cells (hMSCs),” Langenbeck's Archives of Surgery, vol. 394, no. 3, pp. 495–502, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. J. Liu and R. H. Hurt, “Ion release kinetics and particle persistence in aqueous nano-silver colloids,” Environmental Science and Technology, vol. 44, no. 6, pp. 2169–2175, 2010. View at Publisher · View at Google Scholar
  24. M. Halter, J. L. Almeida, A. Tona, K. D. Cole, A. L. Plant, and J. T. Elliott, “A mechanistically relevant cytotoxicity assay based on the detection of cellular GFP,” Assay and Drug Development Technologies, vol. 7, no. 4, pp. 356–365, 2009. View at Publisher · View at Google Scholar · View at Scopus
  25. C. Carlson, S. M. Hussein, A. M. Schrand et al., “Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species,” Journal of Physical Chemistry B, vol. 112, no. 43, pp. 13608–13619, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. P. V. AshaRani, G. L. K. Mun, M. P. Hande, and S. Valiyaveettil, “Cytotoxicity and genotoxicity of silver nanoparticles in human cells,” ACS Nano, vol. 3, no. 2, pp. 279–290, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. A. P. Leonov, J. Zheng, J. D. Clogston, S. T. Stern, A. K. Patri, and A. Wei, “Detoxification of gold nanorods by treatment with polystyrenesulfonate,” ACS Nano, vol. 2, no. 12, pp. 2481–2488, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. P. T. Anastas and J. C. Warner, “Twelve Principles of Green Chemistry,” 2010, http://www.epa.gov/sciencematters/june2011/principles.htm.
  29. P. T. Anastas and J. C. Warner, Green Chemistry: Theory and Practice, Oxford University Press, New York, NY, USA, 1998.
  30. D. Philip, “Honey mediated green synthesis of gold nanoparticles,” Spectrochimica Acta A, vol. 73, no. 4, pp. 650–653, 2009. View at Publisher · View at Google Scholar
  31. R. Shukla, S. K. Nune, N. Chanda et al., “Soybeans as a phytochemical reservoir for the production and stabilization of biocompatible gold nanoparticles,” Small, vol. 4, no. 9, pp. 1425–1436, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. J. L. Gardea-Torresdey, E. Gomez, J. R. Peralta-Videa, J. G. Parsons, H. Troiani, and M. Jose-Yacaman, “Alfalfa sprouts: a natural source for the synthesis of silver nanoparticles,” Langmuir, vol. 19, no. 4, pp. 1357–1361, 2003. View at Publisher · View at Google Scholar · View at Scopus
  33. S. S. Shankar, A. Rai, A. Ahmad, and M. Sastry, “Controlling the optical properties of lemongrass extract synthesized gold nanotriangles and potential application in infrared-absorbing optical coatings,” Chemistry of Materials, vol. 17, no. 3, pp. 566–572, 2005. View at Publisher · View at Google Scholar · View at Scopus
  34. V. Smuleac, R. Varma, S. Sikdar, and D. Bhattacharyya, “Green synthesis of Fe and Fe/Pd bimetallic nanoparticles in membranes for reductive degradation of chlorinated organics,” Journal of Membrane Science, vol. 379, no. 1-2, pp. 131–137, 2011. View at Publisher · View at Google Scholar
  35. R. Naganawa, N. Iwata, K. Ishikawa, H. Fukuda, T. Fujino, and A. Suzuki, “Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlic,” Applied and Environmental Microbiology, vol. 62, no. 11, pp. 4238–4242, 1996. View at Google Scholar · View at Scopus
  36. P. Tedeschi, A. Maietti, M. Boggian, G. Vecchiati, and V. Brandolini, “Fungitoxicity of lyophilized and spray-dried garlic extracts,” Journal of Environmental Science and Health B, vol. 42, no. 7, pp. 795–799, 2007. View at Publisher · View at Google Scholar · View at Scopus
  37. M. S. Rahman, “Allicin and other functional active components in garlic: health benefits and bioavailability,” International Journal of Food Properties, vol. 10, no. 2, pp. 245–268, 2007. View at Publisher · View at Google Scholar
  38. K. Srinivasan, “Spices as influencers of body metabolism: an overview of three decades of research,” Food Research International, vol. 38, no. 1, pp. 77–86, 2005. View at Publisher · View at Google Scholar
  39. M. D. Abramoff, P. J. Magalhaes, and S. Ram, “Image processing with imageJ,” Biophotonics International, vol. 11, no. 7, pp. 36–41, 2004. View at Google Scholar
  40. N. R. Jana, L. Gearheart, and C. J. Murphy, “Wet chemical synthesis of high aspect ratio cylindrical gold nanorods,” Journal of Physical Chemistry B, vol. 105, no. 19, pp. 4065–4067, 2001. View at Publisher · View at Google Scholar · View at Scopus
  41. D. K. Bhui, H. Bar, P. Sarkar, G. P. Sahoo, S. P. De, and A. Misra, “Synthesis and UV-vis spectroscopic study of silver nanoparticles in aqueous SDS solution,” Journal of Molecular Liquids, vol. 145, no. 1, pp. 33–37, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. A. Šileikaite, J. Puišo, I. Prosyčevas, and S. Tamulevičius, “Investigation of silver nanoparticles formation kinetics during reduction of silver nitrate with sodium citrate,” Medziagotyra, vol. 15, no. 1, pp. 21–27, 2009. View at Google Scholar
  43. N. R. Jana, Y. Chen, and X. Peng, “Size- and shape-controlled magnetic (Cr, Mn, Fe, Co, Ni) oxide nanocrystals via a simple and general approach,” Chemistry of Materials, vol. 16, no. 20, pp. 3931–3935, 2004. View at Publisher · View at Google Scholar
  44. X. Ji, X. Song, J. Li, Y. Bai, W. Yang, and X. Peng, “Size control of gold nanocrystals in citrate reduction: the third role of citrate,” Journal of the American Chemical Society, vol. 129, no. 45, pp. 13939–13948, 2007. View at Publisher · View at Google Scholar · View at Scopus
  45. Y. Sun and Y. Xia, “Shape-controlled synthesis of gold and silver nanoparticles,” Science, vol. 298, no. 5601, pp. 2176–2179, 2002. View at Publisher · View at Google Scholar · View at Scopus
  46. X. C. Jiang and M. P. Pileni, “Gold nanorods: influence of various parameters as seeds, solvent, surfactant on shape control,” Colloids and Surfaces A, vol. 295, no. 1–3, pp. 228–232, 2007. View at Publisher · View at Google Scholar · View at Scopus
  47. M. B. Kasture, P. Patel, A. A. Prabhune, C. V. Ramana, A. A. Kulkarni, and B. L. V. Prasad, “Synthesis of silver nanoparticles by sophorolipids: effect of temperature and sophorolipid structure on the size of particles,” Journal of Chemical Sciences, vol. 120, no. 6, pp. 515–520, 2008. View at Publisher · View at Google Scholar · View at Scopus
  48. J. N. Losso and S. Nakai, “Molecular size of garlic fructooligosaccharides and fructopolysaccharides by matrix-assisted laser desorption ionization mass spectrometry,” Journal of Agricultural and Food Chemistry, vol. 45, no. 11, pp. 4342–4346, 1997. View at Google Scholar · View at Scopus
  49. S. K. Mehta, S. Chaudhary, and M. Gradzielski, “Time dependence of nucleation and growth of silver nanoparticles generated by sugar reduction in micellar media,” Journal of Colloid and Interface Science, vol. 343, no. 2, pp. 447–453, 2010. View at Publisher · View at Google Scholar · View at Scopus
  50. P. Bocchini, C. Andalò, R. Pozzi, G. C. Galletti, and A. Antonelli, “Determination of diallyl thiosulfinate (allicin) in garlic (Allium sativum L.) by high-performance liquid chromatography with a post-column photochemical reactor,” Analytica Chimica Acta, vol. 441, no. 1, pp. 37–43, 2001. View at Publisher · View at Google Scholar · View at Scopus
  51. E. Block, “The chemistry of garlic and onions,” Scientific American, vol. 252, no. 3, pp. 114–119, 1985. View at Google Scholar
  52. M. Cai, J. Chen, and J. Zhou, “Reduction and morphology of silver nanoparticles via liquid-liquid method,” Applied Surface Science, vol. 226, no. 4, pp. 422–426, 2004. View at Publisher · View at Google Scholar
  53. J. C. Love, L. A. Estroff, J. K. Kriebel, R. G. Nuzzo, and G. M. Whitesides, “Self-assembled monolayers of thiolates on metals as a form of nanotechnology,” Chemical Reviews, vol. 105, no. 4, pp. 1103–1169, 2005. View at Publisher · View at Google Scholar · View at Scopus
  54. S. Kittler, C. Greulich, J. Diendorf, M. Köller, and M. Epple, “Toxicity of silver nanoparticles increases during storage because of slow dissolution under release of silver ions,” Chemistry of Materials, vol. 22, no. 16, pp. 4548–4554, 2010. View at Publisher · View at Google Scholar · View at Scopus
  55. M. D. Massich, D. A. Giljohann, A. L. Schmucker, P. C. Patel, and C. A. Mirkin, “Cellular response of polyvalent oligonucleotide—gold nanoparticle conjugates,” ACS Nano, vol. 4, no. 10, pp. 5641–5646, 2010. View at Publisher · View at Google Scholar · View at Scopus
  56. A. Köth, J. Koetz, D. Appelhans, and B. Voit, “‘Sweet’ gold nanoparticles with oligosaccharide-modified poly(ethyleneimine),” Colloid and Polymer Science, vol. 286, no. 11, pp. 1317–1327, 2008. View at Publisher · View at Google Scholar · View at Scopus
  57. Y. N. Rao, D. Banerjee, A. Datta, S. K. Das, R. Guin, and A. Saha, “Gamma irradiation route to synthesis of highly re-dispersible natural polymer capped silver nanoparticles,” Radiation Physics and Chemistry, vol. 79, no. 12, pp. 1240–1246, 2010. View at Publisher · View at Google Scholar · View at Scopus
  58. I. Sur, D. Cam, M. Kahraman, A. Baysal, and M. Culha, “Interaction of multi-functional silver nanoparticles with living cells,” Nanotechnology, vol. 21, no. 17, Article ID 175104, 2010. View at Publisher · View at Google Scholar · View at Scopus
  59. C. Marambio-Jones and E. M. V. Hoek, “A review of the antibacterial effects of silver nanomaterials and potential implications for human health and the environment,” Journal of Nanoparticle Research, vol. 12, no. 5, pp. 1531–1551, 2010. View at Publisher · View at Google Scholar · View at Scopus
  60. V. K. Sharma, R. A. Yngard, and Y. Lin, “Silver nanoparticles: green synthesis and their antimicrobial activities,” Advances in Colloid and Interface Science, vol. 145, no. 1-2, pp. 83–96, 2009. View at Publisher · View at Google Scholar · View at Scopus
  61. L. Kvítek, A. Panáček, J. Soukupová et al., “Effect of surfactants and polymers on stability and antibacterial activity of silver nanoparticles (NPs),” Journal of Physical Chemistry C, vol. 112, no. 15, pp. 5825–5834, 2008. View at Publisher · View at Google Scholar
  62. S. Shrivastava, T. Bera, A. Roy, G. Singh, P. Ramachandrarao, and D. Dash, “Characterization of enhanced antibacterial effects of novel silver nanoparticles,” Nanotechnology, vol. 18, no. 22, Article ID 225103, 2007. View at Publisher · View at Google Scholar · View at Scopus
  63. K. Prasad, V. A. Laxdal, M. Yu, and B. L. Raney, “Antioxidant activity of allicin, an active principle in garlic,” Molecular and Cellular Biochemistry, vol. 148, no. 2, pp. 183–189, 1995. View at Publisher · View at Google Scholar · View at Scopus
  64. E. I. Astashkin, O. A. Khokhlova, N. A. Til'kunova, D. Y. Zalepugin, M. G. Glezer, and S. V. Grachev, “Allicin suppresses the production of oxygen radicals by human neutrophils induced by various stimulating agents.,” Doklady Biological Sciences, vol. 389, pp. 188–191, 2003. View at Google Scholar · View at Scopus