Journal of Nanomaterials / 2012 / Article / Fig 5

Research Article

In Vitro Biocompatibility of Endodontic Sealers Incorporating Antibacterial Nanoparticles

Figure 5

The effect of AH+, Epiphany, and GuttaFlow endodontic sealers on TNFα secretion in the RAW macrophage cell line. Mitochondrial activity was normalized to the control without sealers stimulation. Stimulated macrophages (with heat-killed P. gingivalis) with and without the various endodontic sealers were cultured for 24 hrs in the presence of heat-killed P. gingivalis. The secreted TNFα levels in the media were analyzed by ELISA. The results are expressed as the mean + SD. Statistically significant differences between the control (media) and the different groups are indicated by asterisks ( 𝑃 < 0 . 0 5 ) and 𝑛 = 8 wells.