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Journal of Nanomaterials
Volume 2012, Article ID 896562, 9 pages
http://dx.doi.org/10.1155/2012/896562
Research Article

Functionalization of Mesoporous Silicon Nanoparticles for Targeting and Bioimaging Purposes

1School of Pharmacy, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland
2Biocenter Kuopio, 70211 Kuopio, Finland
3Department of Neurology, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland
4CN Services Ltd., Microkatu 1, 70210 Kuopio, Finland
5Department of Physics and Astronomy, University of Turku, Vesilinnantie 5, 20014 Turku, Finland
6Department of Applied Physics, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland

Received 5 April 2012; Accepted 3 June 2012

Academic Editor: Renyun Zhang

Copyright © 2012 Jussi Rytkönen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [37 citations]

The following is the list of published articles that have cited the current article.

  • Päivi J. Kinnari, Maija L.K. Hyvönen, Ermei M. Mäkilä, Martti H. Kaasalainen, Antti Rivinoja, Jarno J. Salonen, Jouni T. Hirvonen, Pirjo M. Laakkonen, and Hélder A. Santos, “Tumour homing peptide-functionalized porous silicon nanovectors for cancer therapy,” Biomaterials, 2013. View at Publisher · View at Google Scholar
  • Dongfei Liu, Bárbara Herranz-Blanco, Ermei Mäkilä, Laura R. Arriaga, Sabiruddin Mirza, David A. Weitz, Niklas Sandler, Jarno Salonen, Jouni Hirvonen, and Hélder A. Santos, “Microfluidic Templated Mesoporous Silicon–Solid Lipid Microcomposites for Sustained Drug Delivery,” ACS Applied Materials & Interfaces, pp. 131113102426008, 2013. View at Publisher · View at Google Scholar
  • N. Daldosso, A. Ghafarinazari, P. Cortelletti, L. Marongiu, M. Donini, V. Paterlini, P. Bettotti, R. Guider, E. Froner, S. Dusi, and M. Scarpa, “Orange and blue luminescence emission to track functionalized porous silicon microparticles inside the cells of the human immune system,” Journal of Materials Chemistry B, vol. 2, no. 37, pp. 6345, 2014. View at Publisher · View at Google Scholar
  • Petri A. Turhanen, “Synthesis of triple bond containing 1-hydroxy-1,1-bisphosphonic acid derivatives to be used as precursors in "click" chemistry: 2 examples,” The Journal of Organic Chemistry, pp. 140610124615000, 2014. View at Publisher · View at Google Scholar
  • Hélder A Santos, Ermei Mäkilä, Anu J Airaksinen, Luis M Bimbo, and Jouni Hirvonen, “Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications,” Nanomedicine, vol. 9, no. 4, pp. 535–554, 2014. View at Publisher · View at Google Scholar
  • Simo Näkki, Jussi Rytkönen, Tuomo Nissinen, Cristina Florea, Joakim Riikonen, Paul Ek, Hongbo Zhang, Hélder A. Santos, Ale Närvänen, Wujun Xu, and Vesa-Pekka Lehto, “Improved stability and biocompatibility of nanostructured silicon drug carrier for intravenous administration,” Acta Biomaterialia, 2014. View at Publisher · View at Google Scholar
  • Frédérique Cuninpp. 647–663, 2014. View at Publisher · View at Google Scholar
  • Benjamin R. Horrockspp. 671–681, 2014. View at Publisher · View at Google Scholar
  • Jarno Salonenpp. 909–919, 2014. View at Publisher · View at Google Scholar
  • J. Salonen, and E. Mäkilä, “Thermal stabilization of porous silicon for biomedical applications,” Porous Silicon for Biomedical Applications, pp. 21–34, 2014. View at Publisher · View at Google Scholar
  • A.J. Airaksinen, “Radiolabeled porous silicon for bioimaging applications,” Porous Silicon for Biomedical Applications, pp. 253–269, 2014. View at Publisher · View at Google Scholar
  • V.-P. Lehto, and J. Riikonen, “Drug loading and characterization of porous silicon materials,” Porous Silicon for Biomedical Applications, pp. 337–355, 2014. View at Publisher · View at Google Scholar
  • J-H. Park, “Porous silicon for tumour targeting and imaging,” Porous Silicon for Biomedical Applications, pp. 403–419, 2014. View at Publisher · View at Google Scholar
  • Chang-Fang Wang, Mirkka P. Sarparanta, Ermei M. Makila, Maija L. K. Hyvonen, Pirjo M. Laakkonen, Jamb J. Salonen, Jouni T. Hirvonen, Anu J. Airaksinen, and Helder A. Santos, “Multifunctional porous silicon nanoparticles for cancer theranostics,” Biomaterials, vol. 48, pp. 108–118, 2015. View at Publisher · View at Google Scholar
  • Ali Dabbagh, Reza Mahmoodian, Basri Johan Jeet Abdullah, Hadijah Abdullah, Mohd Hamdi, and Noor Hayaty Abu Kasim, “Low-melting-point polymeric nanoshells for thermal-triggered drug release under hyperthermia condition,” International Journal of Hyperthermia, pp. 1–10, 2015. View at Publisher · View at Google Scholar
  • Wing Yin Tong, Martin J. Sweetman, Ezzat R. Marzouk, Cara Fraser, Tim Kuchel, and Nicolas H. Voelcker, “Towards a subcutaneous optical biosensor based on thermally hydrocarbonised porous silicon,” Biomaterials, 2015. View at Publisher · View at Google Scholar
  • Steven J. P. McInnes, and Rachel D. Lowe, “Biomedical uses of porous silicon,” Springer Series in Materials Science, vol. 220, pp. 117–162, 2015. View at Publisher · View at Google Scholar
  • Joakim Riikonen, Wujun Xu, and Vesa-Pekka Lehto, “Porous silicon in drug delivery applications,” Springer Series in Materials Science, vol. 220, pp. 163–185, 2015. View at Publisher · View at Google Scholar
  • Charu Bharti, Neha Gulati, Upendra Nagaich, and AshokKumar Pal, “Mesoporous silica nanoparticles in target drug delivery system: A review,” International Journal of Pharmaceutical Investigation, vol. 5, no. 3, pp. 124, 2015. View at Publisher · View at Google Scholar
  • Mónica P.A. Ferreira, Sanjeev Ranjan, Alexandra M.R. Correia, Ermei M. Mäkilä, Sini M. Kinnunen, Hongbo Zhang, Mohammad-Ali Shahbazi, Patrick V. Almeida, Jarno J. Salonen, Heikki J. Ruskoaho, Anu J. Airaksinen, Jouni T. Hirvonen, and Hélder A. Santos, “In vitro and in vivo assessment of heart-homing porous silicon nanoparticles,” Biomaterials, 2016. View at Publisher · View at Google Scholar
  • Olli Gröhn, Vesa-Pekka Lehto, Hanne Laakso, Dalius Kučiauskas, Algirdas Kaupinis, Mikko I. Kettunen, Timo Liimatainen, Mervi Hyvönen, Mindaugas Valius, Tuomo Nissinen, and Simo Näkki, “Tailored Dual PEGylation of Inorganic Porous Nanocarriers for Extremely Long Blood Circulation in Vivo,” ACS Applied Materials and Interfaces, vol. 8, no. 48, pp. 32723–32731, 2016. View at Publisher · View at Google Scholar
  • Jarno Salonen, “Drug Delivery with Porous Silicon,” Handbook of Porous Silicon, pp. 1–14, 2016. View at Publisher · View at Google Scholar
  • Yu. M. Spivak, S. V. Mjakin, V. A. Moshnikov, M. F. Panov, A. O. Belorus, and A. A. Bobkov, “Surface Functionality Features of Porous Silicon Prepared and Treated in Different Conditions,” Journal of Nanomaterials, vol. 2016, pp. 1–8, 2016. View at Publisher · View at Google Scholar
  • Mónica P. A. Ferreira, Sanjeev Ranjan, Sini Kinnunen, Alexandra Correia, Virpi Talman, Ermei Mäkilä, Brianda Barrios-Lopez, Marianna Kemell, Vimalkumar Balasubramanian, Jarno Salonen, Jouni Hirvonen, Heikki Ruskoaho, Anu J. Airaksinen, and Hélder A. Santos, “Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling,” Small, pp. 1701276, 2017. View at Publisher · View at Google Scholar
  • Benjamin R. Horrocks, “Photoluminescent Nanoparticle Derivatization via Porous Silicon,” Handbook of Porous Silicon, pp. 1–12, 2017. View at Publisher · View at Google Scholar
  • Fereshteh Rahimi, Javad Mohammadnejad Arough, Mona Yaghoobi, Hadi Davoodi, Fatemeh Sepehri, and Masood Amirabadizadeh, “A novel approach for osteocalcin detection by competitive ELISA using porous silicon as a substrate,” Biotechnology and Applied Biochemistry, 2017. View at Publisher · View at Google Scholar
  • Tushar Kumeria, Steven J. P. McInnes, Shaheer Maher, and Abel Santos, “Porous silicon for drug delivery applications and theranostics: recent advances, critical review and perspectives,” Expert Opinion on Drug Delivery, pp. 1–16, 2017. View at Publisher · View at Google Scholar
  • Ghafarinazari, Scarpa, Zoccatelli, Comes Franchini, Locatelli, and Daldosso, “Hybrid luminescent porous silicon for efficient drug loading and release,” RSC Advances, vol. 7, no. 11, pp. 6724–6734, 2017. View at Publisher · View at Google Scholar
  • Steven J. P. McInnes, Abel Santos, and Tushar Kumeria, “Porous Silicon Particles for Cancer Therapy and Bioimaging,” Nanooncology, pp. 305–340, 2018. View at Publisher · View at Google Scholar
  • Frédérique Cunin, “Functional Coatings of Porous Silicon,” Handbook of Porous Silicon, pp. 981–996, 2018. View at Publisher · View at Google Scholar
  • Benjamin R. Horrocks, “Photoluminescent Nanoparticle Derivatization via Porous Silicon,” Handbook of Porous Silicon, pp. 1015–1025, 2018. View at Publisher · View at Google Scholar
  • Jarno Salonen, “Drug Delivery with Porous Silicon,” Handbook of Porous Silicon, pp. 1377–1390, 2018. View at Publisher · View at Google Scholar
  • Wei Li, Zehua Liu, Flavia Fontana, Yaping Ding, Dongfei Liu, Jouni T. Hirvonen, and Hélder A. Santos, “Tailoring Porous Silicon for Biomedical Applications: From Drug Delivery to Cancer Immunotherapy,” Advanced Materials, pp. 1703740, 2018. View at Publisher · View at Google Scholar
  • Didem Şen Karaman, Mirkka P. Sarparanta, Jessica M. Rosenholm, and Anu J. Airaksinen, “Multimodality Imaging of Silica and Silicon Materials In Vivo,” Advanced Materials, pp. 1703651, 2018. View at Publisher · View at Google Scholar
  • Juan Fernando Cadavid-Vargas, Pablo Maximiliano Arnal, Ruth Dary Mojica Sepúlveda, Andrea Rizzo, Delia Beatriz Soria, and Ana Laura Di Virgilio, “Copper complex with sulfamethazine and 2,2′-bipyridine supported on mesoporous silica microspheres improves its antitumor action toward human osteosarcoma cells: cyto- and genotoxic effects,” BioMetals, 2018. View at Publisher · View at Google Scholar
  • E. M. Shchukina, M. Graham, Z. Zheng, and D. G. Shchukin, “Nanoencapsulation of phase change materials for advanced thermal energy storage systems,” Chemical Society Reviews, 2018. View at Publisher · View at Google Scholar
  • Sandhya Sanand, Anshika Tyagi, Sandeep Kumar, and Gautam Kaul, “Smart Mesoporous Nanomaterials With Improved Therapeutic Applications,” Multifunctional Nanocarriers for Contemporary Healthcare Applications, pp. 431–447, 2018. View at Publisher · View at Google Scholar