Functionalization of Mesoporous Silicon Nanoparticles for Targeting and Bioimaging Purposes

Table 1

The hydrodynamic size, polydispersity index (PDI), and zeta-potential of the UnTHCPSi nanoparticles with different PEGylations. O-PEG is adsorbed to UnTHCPSi-NP surface while C-PEG is covalently bound with amide linkage.

UnTHCPSi-NP PEGylation	Hydrodynamic size (nm)	PDI	Zeta-potential (mV)
none	139.6 ± 0.7	0.082 ± 0.011	−31.7 ± 0.4
O-PEG 5k Da	137.6 ± 1.2	0.093 ± 0.006	−28.7 ± 0.1
O-PEG 10 kDa	145.3 ± 1.2	0.089 ± 0.006	−26.6 ± 0.8
O-PEG 20 kDa	146.9 ± 1.6	0.079 ± 0.017	−25.6 ± 0.3
C-PEG 5 kDa	134.5 ± 1.0	0.111 ± 0.004	−35.5 ± 0.2
C-PEG 10 kDa	146.6 ± 0.6	0.081 ± 0.024	−32.7 ± 0.7
C-PEG 20 kDa	152.8 ± 1.5	0.109 ± 0.036	−29.0 ± 0.5

The values are represented as an average of three measurements ± standard deviation.