Development of Lecithin Nanoemulsion Based Organogels for Permeation Enhancement of Metoprolol through Rat Skin

Table 1

Formulation of the different types of metoprolol nanoemulsions.

Formulation	Metoprolol tartrate (mg)	Lecithin 170 (g)	Lecithin 200 (g)	Lecithin 100p (g)	Isopropyl myristate (g)	Butanol (mL)	Isopropyl alcohol (mL)	n-Propanol (mL)
F1	40	0.64	—	—	0.96	—	0.3	—
F2	80	0.48	—	—	0.72	—	1.1	—
F3	100	0.4	—	—	0.6	—	1.4	—
F4	10	0.64	—	—	0.96	—	—	0.4
F5	20	0.64	—	—	0.96	—	—	0.2
F6	40	0.64	—	—	0.96	—	—	0.6
F7	60	0.64		—	0.96	—	—	0.2
F8	40	—	0.64	—	0.96	—	—	0.3
F9	40	—		0.64	0.96	—	—	0.8
F10	131	—	0.51	—	0.17	—	—	0.65
F11	40	—	—	—	—	—	—	—
F12	80	0.64	—	—	0.96	—	0.4	—
F13	80	0.4	—	—	0.6	—	0.4	—
F14	40	—	0.51	—	0.17	—	—	0.4
F15	40	0.48	—	—	1.12	—	—	0.6
F16	40	0.8	—	—	0.8	—	—	0.1
F17	40	0.64	—	—	0.96	0.7	—	—