| | Name and characteristics | Structure |
| Nifedipine
Dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Appearance: a yellow crystalline powder
Molecular weight: 346.3
Solubility: practically insoluble in water, sparingly in dehydrated alcohol, freely in acetone
Indication: calcium channel blocker [23]
Log P: 2.2 [24]
Solubility in PBS (pH 7): 0.0056 g/L [25] |  |
| Carbamazepine
5H-dibenzo[b,f]azepine-5-carboxamide
Appearance: a white crystalline powder
Molecular weight: 236.3
Solubility: practically insoluble in water, soluble in alcohol and acetone
Indication: anticonvulsant and mood-stabilizing [23]
Log P: 2.67 [26] |  |
| PVP
Molecular weight: 29000
Specifications: improving the wettability, dissolution rate, and crystal inhibitor [20, 21, 27] |  |
| Ibuprofen
(RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid
Appearance: a white to off-white crystalline powder
Molecular weight: 206.3
Solubility: practically insoluble in water, very soluble in alcohol and acetone, Chloroform, methyl alcohol, slightly soluble in ethyl acetate.
Indication: anti-inflammatory [23]
Log P: 3.6 [28]
Solubility in PBS (pH 7.4): 25.16 mcg/mL [29] |  |
| PEG-300
Monomer: ethylene oxide
Molecular weight: 285–315
Application: cosolvent
|  |
| Mannitol
(2R,3R,4R,5R)-hexan-1,2,3,4,5,6-hexol
Application: converting the drug nanosuspensions to a stable solid form and easy redispersibility |  |
| HPMC
Molecular weight: 86000
Specifications: improving the wettability, dissolution rate, and crystal inhibitor [18, 19, 27] |  |
|
|
