Table 3: Grading system of macroscopic signs in the in vivo tolerance study of the gelatin nanoparticles.

Control*Free TAMRAGP(+) TAMRA
Time0.5 h4.0 h0.5 h2.0 h4.0 h16.0 h0.5 h2.0 h4.0 h16.0 h

Grade
 Discomfort0000000000
 Cornea0000000000
 Conjunctive0000100010
 Discharge0000101000

.
GP: gelatin nanoparticles; TAMRA: tetramethyl rhodamine.