Table of Contents Author Guidelines Submit a Manuscript
Journal of Nanomaterials
Volume 2013, Article ID 238742, 10 pages
Research Article

Cytocompatibility of Plasma and Thermally Treated Biopolymers

1Department of Solid State Engineering, Institute of Chemical Technology, 166 28 Prague, Czech Republic
2Department of Power Engineering, Institute of Chemical Technology, 166 28 Prague, Czech Republic
3Faculty of Science, J. E. Purkyně University, 400 96 Ústí nad Labem, Czech Republic

Received 3 June 2013; Revised 21 June 2013; Accepted 21 June 2013

Academic Editor: Jiamin Wu

Copyright © 2013 Petr Slepička et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper is focused on the surface characterization of plasma and consequently thermally treated biocompatible polymers. PLLA (poly(L-lactide acid) and PMP (poly-4-methyl-1-pentene) are studied. The influence of Ar plasma treatment on the surface polarity of substrate measured immediately after treatment and during the polymer surface aging is studied. Surface roughness, morphology, wettability, and surface chemistry were determined. Plasma treatment leads to significant changes in PLLA surface morphology and chemistry, with the PMP being slightly affected. The higher resistance to plasma fluence results in smaller ablation of PMP than that of PLLA. The plasma treatment improves cell adhesion and proliferation on the PMP. Plasma treatment of PLLA influences mostly the homogeneity of adhered and proliferated VSMC.