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Journal of Nanomaterials
Volume 2013, Article ID 373414, 7 pages
Research Article

Graphene Oxide Reinforced Polylactic Acid/Polyurethane Antibacterial Composites

1Key Laboratory of Mechanics on Environment and Disaster in Western China, The Ministry of Education of China, Lanzhou 730000, China
2Institute of Solid Mechanics, School of Civil Engineering and Mechanics, Lanzhou University, Lanzhou 730000, China
3School of Stomatology, Lanzhou University, Lanzhou 730000, China
4Department of Stomatology, Traditional Chinese Medicine Hospital of Gansu Province, Lanzhou 730050, China

Received 13 June 2013; Accepted 12 August 2013

Academic Editor: Xingbin Yan

Copyright © 2013 Xiaoli An et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Nanocomposites from PLA/PU containing small concentrations of graphene oxide (GO) were prepared by simple liquid-phase mixing followed by casting. The as-prepared ternary PLA/PU/GO composite films exhibited good antibacterial activity against the gram-positive Staphylococcus aureus and the gram-negative Escherichia coli, due to the excellent antibacterial property of GO sheets with high specific surface area. The addition of GO inhibited the attachment and proliferation of microbes on the film surfaces, resulting in that the PLA/PU/GO composite films show remarkably improved antibacterial activity compared with PLA/PU composite film. The inhibition efficiency is proportional to the amount of GO. Furthermore, PLA/PU/GO composite fibrous paper was fabricated using electrospinning and exhibited good biocompatibility. The addition of GO does not destroy normal cell’s proliferation and differentiation. PLA/PU/GO composites with good antibacterial activity and biocompatibility make it attractive for the environmental and clinical applications and also provide a candidate for future application of tissue engineering.