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Journal of Nanomaterials
Volume 2013 (2013), Article ID 384717, 11 pages
Research Article

Bioreducible PEI-siRNA Nanocomplex for Liver Cancer Therapy: Transfection, Biodistribution, and Tumor Growth Inhibition In Vivo

1Department of Imaging, Tongji Hospital, Tongji University, Shanghai 200065, China
2Department of Nuclear Medicine, Shanghai Seventh People’s Hospital, Shanghai 200137, China
3Translational Medicine Research Centre and Central Laboratory, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai 200040, China
4The Institute for Advanced Materials and Nano Biomedicine, School of Medicine, Tongji University, Shanghai 200092, China
5School of Life Sciences and Technology, Tongji University, Shanghai 200092, China

Received 21 May 2012; Revised 11 December 2012; Accepted 11 December 2012

Academic Editor: Takuya Tsuzuki

Copyright © 2013 Wei Xia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [4 citations]

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  • Peng Zhao, Chao Lin, Yuanliang Huang, and Shuhong Wang, “In Vitro and In Vivo Osteoconductivity of Bone Marrow Stromal Cells in Biomimetic Polycaprolactone/Calcium Phosphate Cement Composites,” Journal Of Biomaterials And Tissue Engineering, vol. 3, no. 5, pp. 512–522, 2013. View at Publisher · View at Google Scholar
  • S. Sajeesh, Tae Yeon Lee, Sun Woo Hong, Pooja Dua, Jeong Yong Choe, Dong-ki Lee, Aeyeon Kang, Wan Soo Yun, Changsik Song, Sung Ha Park, Soyoun Kim, and Chiang Li, “Long dsRNA-Mediated RNA Interference and Immunostimulation: A Targeted Delivery Approach Using Polyethyleneimine Based Nano-Carriers,” Molecular Pharmaceutics, pp. 140220114128006, 2014. View at Publisher · View at Google Scholar
  • Dan Li, Xin Tang, Benjamin Pulli, Chao Lin, Peng Zhao, Jian Cheng, Zhongwei Lv, Xueyu Yuan, Qiong Luo, Haidong Cai, and Meng Ye, “Theranostic nanoparticles based on bioreducible polyethylenimine-coated iron oxide for reduction-responsive gene delivery and magnetic resonance imaging,” International Journal of Nanomedicine, vol. 9, pp. 3347–3361, 2014. View at Publisher · View at Google Scholar
  • Anish Babu, Ranganayaki Muralidharan, Narsireddy Amreddy, Meghna Mehta, Anupama Munshi, and Rajagopal Ramesh, “Nanoparticles for siRNA-Based Gene Silencing in Tumor Therapy,” IEEE Transactions on NanoBioscience, vol. 15, no. 8, pp. 849–863, 2016. View at Publisher · View at Google Scholar