Bioreducible PEI-siRNA Nanocomplex for Liver Cancer Therapy: Transfection, Biodistribution, and Tumor Growth Inhibition In Vivo

Figure 6

(a) H&E staining shows growth inhibition of HepG2 cells in tumor tissue after intratumoral injection of SS-PEI/VEGF-siRNA complexes, compared to 25 kDa-branched PEI(B-PEI)/siRNA and blank; (b) VEGF staining shows the levels of VEGF protein expression after intratumoral injection of SS-PEI/VEGF-siRNA complexes; (c) CD34 staining shows the levels of CD34 protein expression after the transfection of SS-PEI/VEGF-siRNA. These images are 400x magnifications. (Scale bar: 20 μm).