A Mucoadhesive Electrospun Nanofibrous Matrix for Rapid Oramucosal Drug Delivery

Table 9

Molecular mechanics evaluation of the surface-to-volume ratio and density of pure polymers and blends.

Molecular complex	Surface area (Å^2)	Volume (Å^3)	SVR^#	Mass (amu)	Density (amu/Å^3)
HPMC	1374.70	2655.35	0.5177	993.15	0.3740
PVA	785.80	1327.24	0.5920	442.55	0.3334
Glycerol	982.04	1333.36	0.7365	368.36	0.2762
HPMC/PVA	1548.78	3476.73	0.4454	1435.69	0.4129
HPMC/GLY	1436.69	3247.83	0.4423	1361.53	0.4192
HPMC/PVA/GLY	1624.86	4052.57	0.4009	1804.07	0.4452

#SVR: surface-to-volume ratio.