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Journal of Nanomaterials
Volume 2013, Article ID 972834, 5 pages
Research Article

Facile Synthesis and Characterization of Au Nanoclusters-Silica Fluorescent Composite Nanospheres

State Key Laboratory of Agricultural Microbiology, College of Science, Institute of Chemical Biology, Huazhong Agricultural University, Wuhan 430070, China

Received 13 June 2013; Revised 6 September 2013; Accepted 9 September 2013

Academic Editor: Lavinia Balan

Copyright © 2013 Huiping Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We developed a novel method for the synthesis of Au nanoclusters (NCs) silica fluorescent composite nanospheres by mixing the as-prepared bovine serum albumin (BSA) protected Au NCs with amino-modified silica spheres in acetate buffer solution. The products were characterized by high-resolution transmission electron microscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), fluorescent microscope imaging (FLMI), and dynamic light scattering (DLS) measurements. The proposed method was simple, efficient, and inexpensive. In addition, the composite nanospheres exhibited favorable water-dispersible, stable, and fluorescent properties, potentially leading to further applications in chemical and biological sensors. A reasonable mechanism was also proposed for the formation of composite nanospheres.