Hyaluronate Targeted Solid Lipid Nanoparticles of Etoposide: Optimization and In Vitro Characterization

Table 2

Different formulations of SLNs loaded with etoposide proposed by Design-Expert software according to an irregular fraction factorial design.

Formulation code	Cetyl alcohol/amine ratio	Lipid/HA ratio	Amine type	Organic/aqueous phase percent
C2L1.5DO20	2	1.5	DDA	20
C1L3SO20	1	3	SA	20
C1L3DO20	1	3	DDA	20
C2L3DO10	2	3	DDA	10
C1L3SO10	1	3	SA	10
C1L1.5SO10	1	1.5	SA	10
C1L1.5DO20	1	1.5	DDA	20
C2L1.5SO20	2	1.5	SA	20
C1L1.5DO10	1	1.5	DDA	10
C2L3DO20	2	3	DDA	20
C2L3SO10	2	3	SA	10
C2L1.5SO10	2	1.5	SA	10